Mentoring and research in patient-oriented medicine

描述(由申请人提供)：补充和替代医学(CAM)中以患者为导向的转化研究缺乏资金、机构和智力资源。下一代CAM研究人员将受益于经验丰富的中期临床研究人员的专注指导。这项拟议的以患者为导向的研究的K24职业中期研究员奖将为Bruce Barrett医学博士提供保护时间，以稳定和扩大他的研究计划，并将指导扩大到初级CAM研究人员。巴雷特博士计划在下一个申请周期(截止日期为2011年1月25日)向NCCAM提交T32 NRSA院校研究培训补助金的申请。这笔机构培训赠款将允许在威斯康星大学医学和公共卫生学院(UW SMPH)开发以CAM为目标的研究培训计划。巴雷特博士是威斯康星州州立大学医学院的终身副教授，在研究、出版、教学和指导方面有着良好的记录。他的K23职业发展助学金和随后的两个R01研究助学金来自NCCAM。他目前领导着华盛顿大学初级保健研究奖学金，拥有6个博士后培训职位，由卫生资源和服务管理局的T32 NRSA资助。拟议的K24和T32赠款将通过家庭医学部(DFM)管理。DFM和UW SMPH是同类部门和机构中实力最强、最成功的。巴雷特博士指导初级教师、博士后研究员、住院医师、医学生和研究生。巴雷特博士的几名学员目前正在从事CAM研究。这笔资金将使巴雷特博士能够巩固和扩大他的指导计划，并开发和提交一份T32申请，要求在华盛顿大学SMPH DFM开展一项关于CAM研究的机构培训计划。结合现有的资源和声誉，这将吸引越来越多的最合格和最有前途的未来CAM研究人员。有了这笔赠款，巴雷特博士将获得大量的培训机会，以发展他的知识、技能和经验，以增强他负责任地进行以患者为导向的翻译CAM研究的能力。拟议的研究将建立在先前研究的基础上，特别是由NCCAM资助的两项成功的R01研究。拟议的具体研究的首要目标是研究临床交互作用对后续疾病结局的潜在影响。项目将包括：1)开发和验证对现有录像临床行为的交互分析方法，以及2)创新的贝叶斯中介分析方法，以解释最近完成的R01研究的结果。这笔拟议的K24赠款将支持补充、替代和综合医学的研究计划，这是一个资金不足和代表性不足的医学研究领域，并将支持和促进下一代CAM研究人员的发展。 公共卫生相关性：这项以患者为导向研究的职业生涯中期研究人员奖将支持Bruce Barrett医学博士追求：1)为对补充和替代医学感兴趣的有前途的年轻研究人员提供专门的指导；2)扩大他的研究计划。建议的具体研究将扩大关于以患者为导向的临床互动的性质和影响的知识。

DESCRIPTION (provided by applicant): Patient-oriented translational research in complementary and alternative medicine (CAM) suffers from a lack of financial, institutional, and intellectual resources. The next generation of CAM researchers will benefit from the dedicated mentorship of experienced midcareer clinical investigators. This proposed K24 Midcareer Investigator Award in Patient-Oriented Research will provide Bruce Barrett MD PhD with protected time to stabilize and expand his research program, and to extend mentorship to junior CAM researchers. Dr. Barrett plans to submit an application to NCCAM for a T32 NRSA Institutional Research Training Grant for the next application cycle (due January 25, 2011). This institutional training grant will allow the development of a CAM-targeted research training program at the University of Wisconsin School of Medicine and Public Health (UW SMPH). Dr. Barrett is a tenured Associate Professor at the UW SMPH, with a strong record of research, publication, teaching and mentoring. His K23 career development grant and two subsequent R01 research grants came from NCCAM. He currently leads the UW Primary Care Research Fellowship, with six post-doctoral training positions funded by a T32 NRSA from the Health Resources and Services Administration. The proposed K24 and T32 grants would be administered through the Department of Family Medicine (DFM). DFM and UW SMPH are among strongest and most successful of comparable departments and institutions. Dr. Barrett mentors junior faculty, post-doctoral fellows, resident physician, medical students and graduate students. Several of Dr. Barrett's mentees are currently engaged in CAM research. Funding of this grant would allow Dr. Barrett to solidify and expand his mentoring program, and to develop and submit a T32 application for an institutional training program in CAM research at UW SMPH DFM. Combined with existing resources and reputation, this would attract an increasing pool of the most qualified and promising future CAM researchers. With this grant Dr. Barrett would undertake substantive training opportunities to develop his knowledge, skills, and experience to enhance his ability to responsibly conduct patient oriented translational CAM research. The proposed research will build upon findings from previous research, especially two successful NCCAM-funded R01 studies. The overarching goal of the proposed specific research is to study potential influences of clinical interaction on subsequent illness outcomes. Projects will include: 1) development and validation of an interaction analysis approach to existing videotaped clinical behaviors, and 2) an innovative Bayesian mediation analysis approach to explain findings of recently completed R01 research. This proposed K24 grant would support a program of research in complementary, alternative and integrative medicine, an under-funded and under-represented area of medical research, and would support and facilitate the development of the next generation of CAM researchers. PUBLIC HEALTH RELEVANCE: This Midcareer Investigator Award in Patient-Oriented Research will support Bruce Barrett MD PhD in his quest to: 1) provide dedicated mentoring to promising young researchers with interest in complementary and alternative medicine, and 2) expand his research program. The specific research proposed would expand knowledge regarding the nature and impact of patient-oriented clinical interaction.