2012 Cellular and Molecular Fungal Biology Gordon Research Conference

描述（由申请人提供）：本提案要求部分支持将于2012年6月17日至22日在Holderness学校举行的戈登细胞和分子真菌生物学研究会议。会议的长远目标是在研究人员之间传播有关真菌生物学的信息，以增加我们对基本真菌生物学的集体理解及其在社会重要问题上的应用。真菌是一种优秀的真核生物模式，所以这次会议的大部分内容都将围绕美国国立综合医学科学研究所的目标展开。此外，真菌会引起重大的人类疾病，因此许多研究也将解决美国国立卫生研究院过敏和传染病研究所的利益。这次会议的具体目的是召开

DESCRIPTION (provided by applicant): This proposal requests partial support for the Gordon Research Conference on Cellular and Molecular Fungal Biology to be held at the Holderness School, June 17-22, 2012. The broad and long-term goal of the conference is to spread information about fungal biology among researchers to increase our collective understanding of basic fungal biology and its application to socially important problems. Fungi are excellent eukaryotic model organisms, so much of the conference will be central to the aims of NIH-National Institute of General Medical Science. Furthermore, fungi cause significant human disease, so much of the research presented will also address the interests of the NIH-National Institute of Allergy and Infectious Disease. The specific aim of this meeting will be to convene 52 speakers who represent the leading edge of fungal research with a total of ca. 130-140 participants, most of whom will present posters, for a five-day conference in a setting with few distractions. The oral and poster sessions are designed to emphasize discussion and networking, and evaluations from past conferences demonstrate the effectiveness of this format. The 2012 meeting will combine both newer and core topics to this conference such as systems biology, population and evolutionary genomics, pathogenesis, symbiosis, cell biology and gene expression including RNA control. The significance of this application is the demonstrated effect of this conference in accelerating research in the international fungal biology community, including prevention and treatment of disease. The health relatedness of this application centers on the role of fungi in human disease, including three of the most important diseases of transplant patients, candidiasis, cryptococcosis and aspergillosis, as well as systemic fungal diseases such as histoplasmosis. PUBLIC HEALTH RELEVANCE: Project Narrative: The health relatedness of this application concerns both the role that fungi play in human disease and the role that fungi play in understanding the fundamental features of eukaryotic biology. Knowledge of the biology of fungi is essential to the prevention of fungal disease by illuminating basic features of fungal development, and is essential to treatment of fungal disease by identifying targets for pharmaceuticals and molecular candidates for vaccines. Use of fungi as model organisms continues to speed our understanding of essential features of all complex life, including humans, through study of basic cellular and molecular processes.