MICROBIOLOGICAL REAGENT AND SAMPLE DISTRIBUTION

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 微生物学分部是全世界艾滋病研究界SIV试剂的主要来源。 试剂包括含有SIV序列的重组质粒克隆、突变克隆、病毒原液、动物滴度病毒原液和血清。 试剂通过NIH AIDS Repository分发，并直接从微生物学部门的仓库分发。 Desrosiers实验室一直是NIH AIDS Repository最重要的贡献者之一; NIH Repository已经存放并分发了21种试剂。 微生物学司也继续是其他试剂的主要来源，包括松鼠猴疱疹病毒和恒河猴鼻病毒、各种疱疹病毒克隆DNA、早期传代恒河猴成纤维细胞系、221细胞系、SEAP报告细胞系和各种其他试剂。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The Division of Microbiology is a major source of SIV reagents to the AIDS research community throughout the world. Reagents include recombinant plasmid clones containing SIV sequences, mutant clones, virus stocks, animal-titered virus stocks, and sera. Reagents are distributed via the NIH AIDS Repository and directly from the stores of the Microbiology Division. The Desrosiers laboratory has been one of the most significant contributors to the NIH AIDS Repository; twenty one individual reagents have been deposited and are distributed by the NIH Repository. The Division of Microbiology also continues to be a major source of other reagents, including stocks of herpesvirus saimiri and rhesus monkey rhadinovirus, assorted herpesvirus cloned DNAs, early passage rhesus monkey fibroblast cell lines, the 221 cell line, SEAP reporter cell lines and assorted other reagents.