Establishing the Coordinated Consortium of Networks (CoCoNet)

描述（由申请人提供）：该倡议将创建一个正式的、协调的区域实践研究网络联盟，称为CoCoNet（协调网络联盟），该联盟将包括来自该国4个不同地区的广泛实践、临床医生和患者。椰子网将能够利用区域网络内可能的密切个人关系和质量监督，同时开展可推广到更大人群的研究。由于过程相似（例如，所有5个区域网络都雇用实践增强助理）和先前的研究合作，椰子网将能够快速响应医疗保健研究和质量机构提供的研究和开发机会，并通过嵌入区域学习社区的特定质量改进过程有效地将研究转化为实践。新的联盟还将包括一个独立的协调中心Westat，其中4个区域网络曾与该中心合作过至少一个先前的项目。一个单独的协调中心的参与将减轻主要研究人员的行政负担，使他们有更多的时间来规划和进行研究。必要时，还可以将干预部分与具体项目的数据管理和分析职能分开，减少某些形式的偏见。在隶属于5个区域网络和Westat的4个学术卫生中心中，CoCoNet将能够接触到每个可能领域的内容和方法专家。首席研究员是该国最受尊敬的基于实践的研究人员之一，他为指导CoCoNet做好了充分的准备。在许多方面，这只是区域网络和Westat之间的一个更正式的协议，得到基础设施资金的支持，这个协议已经非正式地存在了好几年。

DESCRIPTION (provided by applicant): This initiative will create a formal, coordinated coalition of regional practice-based research networks called CoCoNet (the Coordinated Coalition of Networks) that will include a broad spectrum of practices, clinicians, and patients from 4 different parts of the country. CoCoNet will be able to take advantage of the close personal relationships and quality oversight possible within regional networks while conducting research that is generalizable to larger populations. Because of the similarities in processes (e.g. all 5 regional networks employ practice enhancement assistants) and prior research collaborations, CoCoNet will be capable of responding quickly to research and development opportunities offered by the Agency for Healthcare Research and Quality and effective in translating research into practice through specific quality improvement processes embedded within regional learning communities. The new coalition will also include an independent Coordinating Center, Westat, with whom 4 of the regional networks have worked on at least one prior project. The involvement of a separate Coordinating Center will reduce the administrative burdens of principal investigators giving them more time to plan and conduct research. It will also make it possible, when desirable, to separate the intervention components from the data management and analysis functions on specific projects, reducing some forms of bias. Among the 4 academic health centers that are affiliated with the 5 regional networks and Westat, CoCoNet will have access to content and methodological experts in every possible field. The Principle investigator, who is one of the most respected practice-based researchers in the country, is well-prepared to direct CoCoNet, which, in many respects, is simply a more formal agreement, supported by infrastructure funding, between regional networks and Westat that has already existed informally for several years. PUBLIC HEALTH RELEVANCE: CoCoNet will conduct high quality primary care research that is generalizable to the population of the United States. It will demonstrate the value of regional network coalitions and Coordinating Centers while further developing methods for translation of research into practice and practice into research within purposefully constructed learning communities.