Indigenous Wellness Research Institute National Center of Excellence

华盛顿大学的土著健康研究所(IWRI)成功地履行了其使命，即解决美洲印第安人和阿拉斯加原住民(AIAN)的健康问题，并通过发展跨学科研究基础设施，与国内和国际主要部落社区和组织建立广泛的伙伴关系，并在最初五年获得1400万美元的研究和培训奖，消除健康差距。华盛顿大学和社会工作学院为研究所的发展提供了肥沃的土壤，并承诺提供大量额外的机构和行政支助。本申请响应RFA-MD-11-003“NIMHD综合卓越中心(P60)”，旨在将IWRI发展成为致力于AIAN健康和健康差距研究的国家综合卓越中心(COE)，并培养一支由NIH资助的AIAN行为科学家队伍。它为IWRI提供了一个极好的机会来巩固其蓬勃发展的基础设施，并加强现有的合作伙伴，使其成为一个充满活力、协同和协作的整体。IWRI的主题重点是对AIAN产生不成比例影响的行为根源健康状况(例如，心血管疾病、肥胖、糖尿病、艾滋病毒/艾滋病、药物滥用和精神疾病)，并以IWRI杰出领导人的理论和经验工作为基础，在过去20年中，他们在AIAN健康相关项目上获得了NIH拨款，与IWRI调查人员和社区合作伙伴的广泛网络一起，一直处于AIAN行为研究的前沿。他们的创新工作强调了历史背景在满足AIAN健康需求方面的重要性，以及影响健康的暴力、药物使用和心理痛苦等共生因素。这些风险因素在主任开创性的原住民压力应对模式中被概念化，该模式将用于指导课程和方案的制定。与研究所的四个主要目标一致，研究所的拟议目标是通过以下方式改善AIAN的健康状况和消除健康差距：(1)在IIAN研究、培训活动和社区能力建设的成功基础上，发展一个综合、全面和集中的跨学科研究基础设施；(2)培养和建立与AIAN部落社区和其他组织的现有伙伴关系，以促进真正的合作研究；(3)在IWRI发展新的和改进现有的研究培训活动，使研究人员准备进行科学严谨和有文化基础的卫生研究；以及(4)加强和巩固AIAN的参与、外联和机构伙伴关系。

The UW's Indigenous Wellness Research Institute (IWRI) has successfully pursued its mission to address American Indian and Alaska Native (AIAN) health and eliminate health disparities by developing a trans-disciplinary research infrastructure, cultivating extensive partnerships with leading national and international tribal communities and organizations, and securing $14 million in research and training awards over its initial five years. The UW and School of Social Work have provided fertile ground for IWRI development and have pledged considerable additional institutional and administrative support. This application, in response to RFA-MD-11-003 "NIMHD Comprehensive Centers of Excellence (P60)" is designed to develop IWRI as a National Comprehensive Center of Excellence (COE) devoted to AIAN health and health disparities research and to develop a cadre of NIH-funded AIAN behavioral scientists. It provides an excellent opportunity for IWRI to consolidate its burgeoning infrastructure and strengthen existing partners into a vibrant, synergistic, collaborative whole. IWRI's thematic focus is on behaviorally rooted health conditions that disproportionately affect AIANS (e.g., cardiovascular disease, obesity, diabetes, HIV/AIDS, substance abuse, and mental illness) and is grounded in the theoretical and empirical work of IWRI's eminent leaders, who have been awarded numerous NIH grants on AIAN health-related projects over the last two decades and, along with the extensive network of IWRI investigators and community partners, have been at the forefront of AIAN behavioral research. Their innovative work emphasizes the importance of historical context in addressing AIAN health needs, as well as the co-occurring factors of violence, substance use, and psychological distress that affect health. These risk factors are conceptualized in the Director's ground-breaking Indigenist Stress-Coping Model, which will be used to guide curriculum and program development. Consistent with the four main objectives of NIMHD Centers, the proposed aims of IWRI are to Improve AIAN health and eliminate health disparities by: (1) developing an integrated, comprehensive, and centralized trans-disciplinary research infrastructure that builds on the successes of IWRI's research, training activities, and community capacity building; (2) cultivating existing and establishing novel partnerships with AIAN tribal communities and other organizations to facilitate truly collaborative research; (3) developing new and enhancing existing research training activities at IWRI that prepare researchers to conduct scientifically rigorous and culturally grounded health research; and (4) strengthening and consolidating AIAN engagement, outreach and institutional partnerships.