TECHNICAL INFORMATION RESEARCH RESOURCES FOR CANCER PREVENTIVE AGENT DEVELOPMENT

该合同的目的是提供各种必要的关键癌症预防研究信息管理功能，以支持FDA为临床试验识别、开发和鉴定用于研究新药(IND)的潜在癌症预防药物。对癌症预防药物开发的支持包括收集和组织来自研究、药物和医学文献的信息；临床前和临床技术项目报告；科学会议；以及根据保密协议向NCI提供的私人行业文件。支持还包括提取和维护技术报告的数据库；提取预防癌症计划的应用材料；为管理管理委员会(MAC)准备特定的化学和生物制剂和一般类别文件以及结构/功能和基因组/蛋白质信息和统计分析；起草外部指导小组、特别强调小组和MAC会议的纪要，以及当前癌症预防制剂开发研究的主题、进展和机会的手稿。

The purpose of the contract is to provide a variety of critical cancer prevention research information management functions necessary to support the identification, development, and qualification of potential cancer preventive agents for investigational new drug (IND) applications to the FDA for clinical trials. Support for cancer preventive agent development includes the gathering and organizing of information from the research, pharmaceutical, and medical literature; preclinical and clinical technical project reports; scientific meetings; and private industry documents provided to the NCI under confidentiality agreements. Support also includes abstracting and maintaining data bases of technical reports; abstracting application materials for the PREVENT Cancer Program; preparing specific chemical and biological agent and general class documents and structure / function and genomic / proteomic informational and statistical analyses for the Management Administrative Committee (MAC); and drafting minutes of the External Steering Panel, the Special Emphasis Panel and MAC meetings and manuscripts of current topics, progress, and opportunities in cancer preventive agent development research.