Serotonin Club Meetings 2012-2016

简介(申请人提供)：5-羟色胺俱乐部成立于1987年，是一个由对5-羟色胺任何方面的研究感兴趣的生物医学科学家组成的国际协会。该俱乐部的一个重要目标是促进青年研究人员，包括学生、博士后研究员和初级研究人员(博士后工作不到3年)参加国际高质量科学会议。 它的中心主题是5-羟色胺。5-羟色胺与物质滥用、疼痛、心血管和胃肠功能、神经发育以及包括成瘾在内的一系列精神疾病有关。吸引不同受众的不仅是5-羟色胺的神经科学及其影响的神经递质系统，还包括5-羟色胺在外周功能中的作用。因此，我们的目标是将对5-羟色胺有共同兴趣的研究人员聚集在一起，以便能够交流其功能的深度，以及重要的新发现。5-羟色胺俱乐部会议的一项新举措是提供一个焦点，并建立对药物滥用的强烈重视，因为它涉及5-羟色胺与其他神经递质系统的相互作用，重要的是，了解5-羟色胺在成瘾疾病中的作用，以及如何将这一系统作为治疗药物滥用的目标。2012年会议的一个关键目标将是通过列入与药物滥用直接相关的专题讨论会来促进这一新倡议。重要的是，5-羟色胺俱乐部的一个主要目标是提供一个充满活力的论坛，帮助该领域的年轻调查人员发展职业生涯。因此，我们计划将NIDA旅行奖的十名获奖者作为专题演讲嘉宾，每十个程序化研讨会中就有一个。此外，这些年轻的研究人员将：1)作为指导计划的一部分；2)能够在许多场合(例如海报会议、休息、午餐和晚宴)与包括该领域的领导者在内的高级研究人员建立网络联系；3)在会议记录中发表他们的工作。选择将基于申请者的资历以及他们的摘要与药物滥用和相关疾病的相关性。5-羟色胺俱乐部的第一次会议将于2012年7月10-12日在法国蒙彼利埃举行。R13申请的主要目的是向这些年轻调查人员提供财政支持，使他们能够出席和参加2012年5-羟色胺俱乐部会议，并支持未来的年轻调查人员参加2014年和2016年的后续会议。 公共卫生相关性：5-羟色胺与物质滥用、疼痛、心血管和胃肠功能、神经发育以及包括成瘾在内的各种精神疾病有关。5-羟色胺俱乐部会议的一项新举措是将重点放在药物滥用问题上，以更好地了解5-羟色胺系统在药物滥用和治疗中的作用，以及它与其他神经递质系统的相互作用。2012年会议的一个主要目标是通过包括几个与药物滥用直接相关的研讨会和支持对药物滥用感兴趣的年轻科学家参加5-羟色胺俱乐部会议来促进这一新倡议。

DESCRIPTION (provided by applicant): The Serotonin Club, founded in 1987, is an international association for biomedical scientists who are interested in research on any aspect of serotonin. An important objective of the Club is to facilitate the involvement of young investigators, comprising students, post-doctoral fellows and junior researchers (less than 3 years past their post-doctoral fellowship) in an international high-quality scientific meeting with serotonin as its central theme. Serotonin has been implicated in substance abuse, pain, cardiovascular and gastrointestinal function, neural development as well as a host of psychiatric diseases, including addiction. A diverse audience is attracted by including not only the neuroscience of serotonin, and the neurotransmitter systems on which it impinges, but also the role of serotonin in peripheral function. Thus, our goal is to bring together researchers with a common interest in serotonin such that the depth of its functions, and importantly, new discoveries, can be communicated. A new initiative of the Serotonin Club Meetings is to provide a focus and build a strong emphasis on substance abuse, as it relates to serotonin's interactions with other neurotransmitter systems, and importantly, to understand serotonin's role in the disease of addiction and how this system can be targeted for the treatment of substance abuse. A key goal of the 2012 meeting will be to foster this new initiative by inclusion of symposia directly related to substance abuse. Importantly, a major goal of the Serotonin Club is to provide a dynamic forum to help develop the careers of young investigators in the field. As such, we plan to include ten recipients of NIDA Travel Awards as featured speakers, one in each of ten programmed symposia. In addition these young investigators will i) be part of a mentoring program, ii) be able to network with senior researchers, including leaders in the field, at many occasion (e.g. poster sessions, breaks, lunches, and dinner banquet); and iii) have their work published in the conference proceedings. Selection will be based on the applicant's credentials and on the relevance of their abstract to drug abuse and related disorders. The first meeting of the Serotonin Club for which funds are sought will be held July 10-12, 2012 in Montpellier, France. The primary aim of this R13 application is to provide financial support to these young investigators to enable them to attend and participate in the 2012 Serotonin Club Meeting as well as to support future young investigators to attend subsequent meetings in 2014 and 2016. PUBLIC HEALTH RELEVANCE: Serotonin has been implicated in substance abuse, pain, cardiovascular and gastrointestinal function, neural development as well as various psychiatric disorders, including addiction. A new initiative of the Serotonin Club Meetings is to focus on substance abuse to better understand the role of the serotonin system, and its interactions with other neurotransmitter systems, in substance abuse and it treatment. A major goal of the 2012 meeting is to foster this new initiative by including several symposia directly related to substance abuse and by supporting the attendance of young scientists, interested in drug abuse, to the Serotonin Club Meeting.