SPATIALLY MODULATED QUANTITATIVE SPECTROSCOPY (SMOQS)

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 我们正在开发一种新的，非接触式的方法，基于空间频域成像原理，使混浊介质的定量光学性质的测定从430-1050 nm。通过测量来自未知样品的宽带反射率作为投影照明图案的空间频率的函数，可以计算绝对吸收和减少的散射系数，而无需存在发色团的先验假设。这种技术被称为空间调制定量光谱（SMoQS）。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. We are developing a novel, non-contact method, based on spatial frequency domain imaging principles, that enables determination of quantitative optical properties of turbid media from 430-1050 nm. Through measuring the broadband reflectance from an unknown sample as a function of the spatial frequency of the projected illumination patterns, the absolute absorption and reduced scattering coefficients can be calculated without a priori assumptions of the chromophores present. This technique is called Spatially Modulated Quantitative Spectroscopy (SMoQS).