DATA MANGEMENT AND STATISTICS CORE

数据管理和生物统计核心(Data Core)为所有六个核心(行政、临床、神经病理学、神经成像、心理社会、教育)以及附属于ADC的个人研究人员执行数据管理和分析。数据核心将纽约大学ADC收集的所有数据保存在一个中央数据库中，将数据传输到国家阿尔茨海默病协调中心(NACC)，为全国所有ADC创建一个通用数据库，并为纽约大学ADC的所有合作研究人员提供实验设计和统计分析方面的咨询和实践帮助。The Rapid 老龄化和痴呆症相关数据的大小、类型和复杂性的增加要求数据核心扩展其功能，以便(1)促进通过互联网的信息交换，(2)引入、应用和开发新的统计方法，以进行全面的数据分析。数据核心的具体目标是： 1.继续提供我们传统的数据管理和统计咨询服务，包括管理和更新中央数据库，提供实验设计和统计分析咨询，并与国家咨询委员会保持密切合作，为所有ADC实施和使用统一数据集(UDS)。 2.进一步开发和维护一个安全的网上数据库，以符合纽约大学制定的机构标准，用于中心内以及中心、国家反腐败中心和其他合作者之间的多用户在线信息交流。我们正在将我们的VisualFoxPro数据库服务器升级为由纽约大学赞助的现代基于Web的医疗管理软件(临床数据库加临床管理)？Velos。 3.在我们的其他核心/中心内部和之间积极发起、发展、参与和指导统计分析。数据核心分析员(包括见习生)被分配到其他核心，以增加相互互动和了解，并促进在设计与ADC相关的研究和分析ADC数据方面的密切合作。Data Core Leader与对协作分析感兴趣的核心分析师和ADC研究人员每两周举行一次会议。我们还积极参与研究论文的撰写。 4.对中心附属研究人员进行数据库利用和相关统计分析方法的培训。已经并将继续通过一个全面的互联网站、详细的教育主题、在线帮助以及每月统计研讨会来实现这一目标。 5.积极参与和牵头拨款申请，以进一步提高数据核心资金水平。

The Data Management and Biostatistics Core (Data Core) performs data management and analysis for all six fellow cores (Administrative, Clinical, Neuropathology, Neuroimaging, Psychosocial, Education), and for individual researchers affiliated with the ADC. The Data Core maintains all data collected by the NYU ADC in a centralized database, transfers data to the National Alzheimer's Coordinating Center (NACC) to create a common database for all ADC's across the country, and offers consultation and hands-on help in experimental design and statistical analysis to all collaborating investigators in the NYU ADC. The rapid increase in the size, the type and the complexity of aging and dementia related data demands that the Data Core expand its functions in order to (1) facilitate information exchange via the Internet, and (2) introduce, apply and develop novel statistical methods for comprehensive data analysis. Data Core Specific Aims are: 1. Continue to provide our traditional data management and statistical consultation services which include managing and updating the centralized Center database, offering consultation on experimental design and statistical analysis, and maintaining close collaboration with the NACC in the implementation and utilization of the uniform data set (UDS) for all ADC's. 2. Further develop and maintain a secure Web-based database, conforming to the institutional standards set by NYU, for multi-user on-line information exchange within the Center and between Centers, NACC and other collaborators. We are upgrading our Visual FoxPro database server to a modern web-based health care management software (clinical database plus clinical management) ¿ Velos, sponsored by NYU. 3. Actively initiate, develop, participate in and direct statistical analyses within and between our fellow cores/centers. Data Core analysts (including student trainees) are assigned to fellow cores to increase mutual interactions and understanding, and foster close collaborations in the design of ADC related studies and the analysis of ADC data. Data Core leader conducts biweekly meetings with Core analysts and ADC researchers interested in collaborative analysis. We also actively participate in research paper writing. 4. Educate Center affiliated researchers on database utilization and related statistical analysis methods. This has been and will continuously be achieved through a comprehensive internet site with detailed education topics and on-line help as well as monthly statistics seminar. 5. Actively participate in as well as lead grant applications to further increase Data Core funding levels.