Improving Kidney Transplant Outcomes Using Normothermic Machine Perfusion

捐赠用于移植的肾脏有损坏的风险，这会阻止器官工作并缩短其寿命。常温机器灌注是一种可以在移植前使含氧血液在正常体温下循环通过供体肾脏的设备。在这样做的时候，它能够使肾脏复苏并防止损伤。我们将确定机器灌注如何实现这种显着的效果，并研究肾损伤的新治疗方法。

Kidneys donated for transplantation are at risk of damage that prevent the organ from working and reduce its lifespan. Normothermic machine perfusion is a device that can circulate oxygenated blood at normal body temperature through a donor kidney prior to transplantation. In doing so it is able to resuscitate the kidney and prevent injury. We will determine how machine perfusion achieves this remarkable effect and investigate new treatments for kidney injury.