International Core

国际核心是专门为支持北卡罗来纳大学、FHL和 技术和创新，包括与国内调查人员协作，促进核心和CFAR之间的协同作用，以及 加强与马拉维、南非、刚果民主共和国等主要国家的艾滋病毒/艾滋病研究合作 在刚果(金)、中国、俄罗斯、中美洲、尼加拉瓜和危地马拉。纯粹的音量和 我们合作网站中艾滋病毒的密度使研究问题得以快速有效地解决 在艾滋病毒流行率较低的地方是不可能的。北卡罗来纳大学CFAR为NIH提供的艾滋病毒支持的很大一部分 研究是为在美国以外进行的工作而来的。这涉及到领导角色在 NIH国际网络，包括HPTN、国际ACTG、CHAVI(艾滋病毒疫苗中心 免疫学)、杀微生物剂试验网络和IMPAACT。北卡罗来纳大学的全球艾滋病计划导致了 在马拉维的利隆圭成立了NIH艾滋病毒临床试验单位(CTU)，被广泛认为是 在NIH网络中工作效率最高。研究人员发起的关于艾滋病毒临床护理和生物学和 与艾滋病毒传播和预防传播有关的社会因素在南非马拉维正在进行， 中国，刚果民主共和国，与俄罗斯；致力于性病和艾滋病毒重叠的研究一直是中国的重点。北卡罗来纳大学 调查人员参加了几乎所有的Fogarty研究培训计划，包括AITRP、 Fogarty非洲法语国家生物伦理中心，ICORTA-TB/AIDS，以及Fogarty Ellison Pre-and 博士后项目。核心提供：支持基础、临床和行为/社会科学 基础设施和能力建设；在国内和在北卡罗来纳大学进行关于制定礼仪的培训、内部审计委员会和 监管；以及考虑国际研究合作提出的一系列伦理挑战。 核心在促进跨核心协作方面发挥了领导作用，指导初级调查人员， 为国际合作者准备手稿和赠款，并传达来自 国际研究。

The International Core is designed specifically to support the international research base of UNC, FHl, and RTI, including collaborating in-country investigators, foster synergy across the Cores and CFARs, and enhance HIV/AIDS research collaborations in key countries: Malawi, South Africa, the Democratic Republic of Congo (DRC), China, Russia, and in Central America, Nicaragua and Guatemala. The sheer volume and density of HIV in our collaborating sites allows research questions to be addressed with speed and efficiency impossible in places with lower HIV prevalence. A substantial part ofthe UNC CFAR's NIH support for HIV research comes for work undertaken outside the United States. This has involved leadership roles in the nternational NIH networks, including HPTN, the International ACTG, the CHAVI (Center for HIV Vaccine Immunology), Microbicide Trials Network and IMPAACT. UNC's global AIDS programs have led to the formation of an NIH HIV Clinical Trials Unit (CTU) in Lilongwe, Malawi, widely viewed as one ofthe best and most productive in the NIH Networks. Investigator-initiated research on HIV clinical care and biological and social factors related to HIV transmission and prevention of transmission is ongoing in Malawi, South Africa, China, the DRC, and Russia; research devoted to STD and HIV overlap has been a focus in China. UNC investigators have participated in virtually all Fogarty research Training Programs including AITRP, the Fogarty Center for Bioethics in Francophone Africa, the ICORTA-TB/AIDS, and the Fogarty Ellison pre- and post-doctoral programs. The Core provides: support for basic, clinical, and behavioral/social science infrastructure and capacity building; training in-country and at UNC in protocol development, IRB, and regulatory; and consideration of a range of ethical challenges raised by international research collaborations. The Core has provided leadership in facilitating cross-Core collaborations, mentoring junior investigators, manuscript and grant preparation for international collaborators, and communicating results from international research.