2013 Lung Development, Injury and Repair Gordon Research Conference & Gordon Rese

描述(由申请人提供)：我们请求资助2013年肺发育、损伤和修复戈登研究会议和首届戈登研究研讨会，会议将分别于8月18-23日和17-18日在汉普郡休斯敦安多弗的普罗科特学院举行。戈登肺发育、损伤和修复研究会议(GRC)旨在为不同的科学家群体提供从基础到临床的研究范围，介绍正常肺内稳态的细胞和分子机制以及这些过程在疾病中如何失调的最新进展。越来越多的人认识到，对正常肺发育至关重要的过程和途径对出生后组织动态平衡非常重要，在肺部疾病中调节失调。慢性阻塞性肺疾病(COPD)、肺纤维化和急性呼吸窘迫综合征(ARDS)等肺部疾病是一个巨大的全球健康问题，全世界有超过6亿人受到影响。据估计，2007年美国有22.5万人死于肺部疾病，其中超过一半(12.4万人)死于慢性阻塞性肺病。2013年关于肺发育、损伤和修复的GRC将强调影响肺发育和出生后组织动态平衡的调控途径的异同，以及这些途径在组织重塑和肺部疾病背景下是如何失调的。主要目标将是：1.提供一个国际论坛，促进在肺发育、损伤和修复等广泛领域工作的知名科学家和年轻科学家之间的互动；2.为学生、博士后实习生和初级教员提供一个网络和职业发展的论坛，并促进他们与知名研究人员的互动；3.鼓励创造性和多学科研究，旨在为肺部疾病患者开发创新和有效的治疗方法。GRC的每一届会议将由一到两名专家领导，他们将促进对当前概念、争议和未来需求的具有挑战性的讨论。除了受邀演讲者的演讲外，年轻的新调查人员还将根据提交的摘要进行简短的演讲。会议还将包括四个海报会议；海报将根据内容分为四个大致相等的组(暂定会议主题目前为发展、损伤、修复和治疗目标/干预)，以进一步加强与会者之间的非正式互动和思想分享。相关的GRS会议专门旨在促进早期调查人员的招聘和参与，并将强调受训人员和青年调查人员之间的指导、互动和网络联系。

DESCRIPTION (provided by applicant): We are requesting funds in partial support of the 2013 Lung Development, Injury and Repair Gordon Research Conference and the inaugural Gordon Research Seminar, to be held from August 18-23rd and 17-18th, respectively, at Proctor Academy in Andover, Hew Hampshire. The Gordon Research Conference (GRC) on Lung Development, Injury and Repair is designed to provide a diverse group of scientists that span the basic to clinical research spectrum with the latest developments on the cellular and molecular mechanisms of normal lung homeostasis and how these processes are dysregulated in disease. There is growing appreciation that processes and pathways critical for normal lung development are important for postnatal tissue homeostasis and are dysregulated in lung disease. Lung diseases such as chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, and acute respiratory distress syndrome (ARDS) represent a huge global health problem, affecting more than 600 million people worldwide. Of the estimated 225,000 deaths attributed to lung disease in the US in 2007, over half (124,000) were due to COPD. The 2013 GRC on Lung Development, Injury and Repair will emphasize similarities and distinctions in regulatory pathways that impact lung development and postnatal tissue homeostasis, and how these pathways are dysregulated in the setting of tissue remodeling and lung disease. Principal objectives will be to 1. Provide an international forum to promote interaction between established and young scientists working in the broad fields of lung development, injury and repair, 2.To provide a forum for networking and career advancement for students, postdoctoral trainees, and junior faculty and facilitate their interaction with established investigators, and 3 To encourage creative and multidisciplinary research aimed at developing innovative and effective therapies for people with lung disease. Each session of the GRC will be led by one or two experts who will promote challenging discussion of current concepts, controversies and future needs. Besides presentations by invited speakers, shorter presentations will be given by young, new investigators based on submitted abstracts. The meeting will also include four poster sessions; posters will be divided into four approximately equal groups based upon content (tentative session topics are presently Development, Injury, Repair, and Therapeutic Targets/Interventions) to further enhance informal interactions and sharing of ideas among participants. The associated GRS meeting is specifically aimed at promoting the recruitment and participation of early stage investigators and will emphasize mentoring, interactions and networking between trainees and young investigators.