Integrative Membrane Physiology in the Post-Genome Era

描述(由申请者提供)：我们申请资助将于2012年9月5日至9日在马萨诸塞州伍兹霍尔海洋生物实验室举行的题为“后基因组时代的整合膜生理学”的国际研讨会。这将是第66届全科生理学家协会(SGP)年会。SGP的年度研讨会长期以来一直被誉为生理学家、细胞生物学家和生物物理学家最具开创性、最具合议性和最具影响力的会议之一，涵盖了所有职业阶段(包括学生、博士后研究员/研究人员以及初级和成熟的研究人员)、专业领域(包括学术、政府、私人和制药)和国家。SGP研讨会的参与者通常不到200人，其规模足够大，足以深入覆盖主题，规模足够小，足以鼓励小组讨论和促进跨学科合作，以解决与膜转运相关的日益复杂的人类健康问题。预算的结构是为了促进这些富有成效的互动，方法是支持特邀发言者的特殊阵容、初级、中级和高级科学家的多样化群体，以及代表不足和处境不利的研究人员的大量出席。为2012年SGP研讨会精心制定了一个非常雄心勃勃的计划，其中包括一个名副其实的离子传输领域的“名人录”。离子通道研究领域的国际公认领导者将发表两场主旨演讲：Michael Welsh博士(HHMI/爱荷华大学)和Robert Kass博士(哥伦比亚大学)。该计划由一个杰出的组织委员会开发，该委员会由膜运输领域的领导人组成，包括J.Nerbonne(华盛顿大学)、L.Ptacek(加州大学旧金山分校)、A.Ribera(科罗拉多大学)和A.Verkman(加州大学旧金山分校)。研讨会将集中讨论4个主要主题：(1)基因组学与离子通道病，(2)遗传模式生物，(3)离子通道复合体，(4)药物发现。将有两个关于药物发现的独立会议，强调将基础科学发现转化为与运输相关的疾病的新疗法的努力。SGP和组委会成员已做好准备，确保本次会议取得成功。研讨会将聚焦于膜运输生理学中最激动人心和最及时的发现，重点是将这项工作转化为新的疗法。 与公共健康相关：我们请求资金支持将于2012年9月5日至9日在马萨诸塞州伍兹霍尔海洋生物实验室举行的题为“后基因组时代的整合膜生理学”的国际研讨会。本次会议将是全科生理学学会(SGP)第66届年会。SGP的年度研讨会有着悠久的历史和声誉，是全世界膜运输生理学家、细胞生物学家和生物物理学家最具创新性的会议之一，涵盖了所有职业阶段(包括学生、博士后研究员、新的研究人员以及知名和资深科学家)和专业领域(包括学术、政府、私人和制药)。

DESCRIPTION (provided by applicant): We request funds to support an international symposium entitled "Integrative Membrane Physiology in the Post-Genome Era" to be held September 5th-9th, 2012, at the Marine Biological Laboratory in Woods Hole, Massachusetts. This will be the 66th Annual Symposium of the Society of General Physiologists (SGP). The annual symposium of the SGP has a long-standing reputation as being one of the most pioneering, collegial, and high-impact meetings for physiologists, cell biologists and biophysicists spanning all career stages (including students, postdoctoral fellows/researchers, and junior and established investigators), professional arenas (including academic, government, private, and pharmaceutical) and nationalities. With typically less than 200 participants, SGP symposia are large enough to provide in-depth coverage of thematic topics and small enough to encourage small- group discussions and foster cross-disciplinary collaborations to tackle the increasingly complex problems in human health related to membrane transport. The budget is structured to facilitate these productive interactions by supporting an exceptional lineup of invited speakers, a diverse group of junior-, intermediate- and senior-level scientists, and a strong attendance of underrepresented and underprivileged researchers. A highly ambitious program comprising a veritable "who's who" in the ion transport field has been carefully developed for the SGP 2012 symposium. There will be two keynote addresses delivered by internationally recognized leaders in ion channel research: Dr. Michael Welsh (HHMI/University of Iowa) and Dr. Robert Kass (Columbia University). The program was developed by a distinguished Organizing Committee consisting of leaders in the membrane transport field, including J. Nerbonne (Washington University), L. Ptacek (University of California - San Francisco), A. Ribera (University of Colorado) and A. Verkman (University of California - San Francisco). The symposium will focus on 4 major themes: (1) Genomics and Ion Channelopathies, (2) Genetic Model Organisms, (3) Ion Channel Complexes, and (4) Drug Discovery. There will be two independent sessions on Drug Discovery, highlighting efforts to translate basic science discoveries into novel therapeutics for transport-related disease. The SGP and members of the Organizing Committee are poised to ensure the success of this meeting. The symposium will focus on the most exciting and timely discoveries in membrane transport physiology, with an overarching emphasis on translating this work into novel therapies. PUBLIC HEALTH RELEVANCE: We request funds to support an international symposium entitled "Integrative Membrane Physiology in the Post-Genome Era" to be held September 5th-9th, 2012, at the Marine Biological Laboratory in Woods Hole, Massachusetts. This meeting will be the 66th Annual Symposium of the Society of General Physiologists (SGP). The annual symposium of the SGP has a long-standing history and reputation of being one of the most innovative meetings for membrane transport physiologists, cell biologists, and biophysicists worldwide that span across all career stages (including students, postdoctoral fellows, new investigators, as well as established and senior scientists) and professional arenas (including academic, government, private, and pharmaceutical).