Systematic Review Core (SRC)/Ian D. Coulter

核心描述该核心，即系统综述核心（SRC）将对这4个项目进行所有的系统综述（SRs）和文献综述。这将包括项目1的完整系统评价和可能的荟萃分析，以及项目2、3和4的不太广泛的评价，我们预计无法进行荟萃分析。审查将由Samueli研究所的一个专家小组与位于兰德公司的南加州循证实践中心（SCEPC）合作进行。Samueli研究所已经开发了一个强大的、高效的和严格的过程来进行系统的审查，并在几乎所有主要的CAM类别中进行了审查[1-15]，使用了一个被称为文献快速证据评估或REAL过程的过程。简单地说，Samueli研究所在一个基于网络的平台上自动化了审查过程，这个平台被称为Mobius Analytics， System review System SRS（版权所有2003-2009 Mobius Analytics Inc., Ottawa, Ontario），以提高审查过程的效率。REAL过程的一个关键优势是Samueli研究所开发了一个系统，不仅可以评估质量的内部有效性，还可以评估外部有效性和模型有效性标准。这一过程是作为一种精简的系统审查系统而发展起来的，它更加客观和以标准为基础，增加了审查过程中评估者之间的可靠性，并创建了一种模型，能够以比大多数系统审查更低的成本以更快速的方式产生证据报告。

Core Description This Core, the Systematic Review Core (SRC) will conduct all the systematic reviews (SRs) and literature reviews for the 4 Projects. These will range from a full systematic review and possible meta-analysis for Project 1 Clinician Based Appropriateness to less extensive reviews for Projects 2,3 and 4 where we are not anticipating being able to conduct meta-analysis. The reviews will be conducted by an expert team at the Samueli Institute with cooperation ofthe Southern California Evidence-Based Practice Center (SCEPC) located at the RAND Corporation. The Samueli Institute has developed a robust, efficient and rigorous process for conducting systematic reviews and has conducted reviews in almost all the major categories of CAM [1-15] using a process referred to as the Rapid Evidence Assessment ofthe Literature or REAL¿ process. Briefly, Samueli Institute has automated the review process on a web-based platform known as Mobius Analytics, Systematic Review System SRS (Copyright 2003-2009 Mobius Analytics Inc., Ottawa, Ontario) to increase the efficiency of the process. A key advantage of the REAL process is that Samueli Institute has developed a system to not only assess internal validity when looking at quality but also external validity and model validity criteria. This process has been developed as a streamlined systematic review system that is more objective and criteria-based, increasing inter-rater reliability in the review process and creating a model that is able to produce evidence reports in a more rapid fashion at a reduced cost than most systematic reviews. The SCEPC is one ofthe premier centers for conducting SRs in the US. It has conducting numerous previous reviews in CAM. The SCEPC was previously awarded a three year grant from NCCAM, administered through AHRQ, to provide technical expertise and conduct systematic reviews for CAM. The SCEPC has collaborated with Samueli Institute on several systematic reviews in the past.