Improving Sleep to Reduce Dementia Risk

我的研究将探索睡眠紊乱和昼夜节律与认知障碍和痴呆症之间的病理生理机制。我将探讨阻塞性睡眠呼吸暂停(OSA)和轻度认知障碍(MCI)患者的睡眠和昼夜节律紊乱对身体和脑血管功能的影响。我还将探讨OSA治疗和光疗法是否可以通过改善睡眠/昼夜功能来阻止甚至改善MCI患者的脑血管功能。

My research will explore the pathophysiological mechanisms that link disturbed sleep and circadian rhythm with cognitive impairment and dementia. I will explore how sleep and circadian disruption in patients with obstructive sleep apnoea (OSA) and mild cognitive impairment (MCI) impact on body and brain vascular function. I will also explore whether OSA treatment and light therapy in MCI patients can arrest or even improve brain vascular function through improved sleep/circadian function.