Improving Stroke Outcomes: Attenuating Progression and Recurrence
Improving Stroke Outcomes: Attenuating Progression and Recurrence
批准号:
nhmrc : 1013612
负责人:
Prof David Howells
金额:
$622.26万
依托单位国家:
澳大利亚
项目类别:
Program Grants
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2016-12-31
中文摘要
中风是第二大最常见的死亡原因和主要原因残疾。几乎没有经过验证的干预措施,因此我们需要引入新的干预措施。我们开发了一个从实验室到床边的项目,以介绍新的卒中治疗方法及其早期二级预防。我们的总体目标是为它们的有效性和安全性提供证据。我们将使用动物中风模型,血液中的标记物来帮助诊断和预测中风结果,并通过成像来帮助选择患者进行几项临床试验。
英文摘要
Stroke is the second most common cause of death and major cause disability. There are few proven interventions, so we need to introduce new ones. We developed a bench to bedside program to introduce new stroke therapies and its early secondary prevention. Our general goal is to provide evidence for their effectiveness and safety. We will use animal stroke models, markers in the blood to help diagnose and predict stroke outcome and imaging to help select patients for several clinical trials.
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会议论文
Imaging and chemical biomarkers for assessing the effectiveness of therapy in the first European investigator-driven clinical trial investigating the benefits of hypothermia in ischaemic stroke patients
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批准号:nhmrc : 1037863
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项目类别:Targeted Calls
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资助金额:$69.92万
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财政年份:2012
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负责人:Prof David Howells
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依托单位:
Uncoupled Research Fellowship
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批准号:nhmrc : 549402
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项目类别:NHMRC Research Fellowships
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资助金额:$51.8万
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财政年份:2009
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负责人:Prof David Howells
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依托单位:
IMPROVING STROKE OUTCOMES: NEW TARGETS AND THERAPIES
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批准号:nhmrc : 454417
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项目类别:Programs
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资助金额:$480.9万
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财政年份:2007
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负责人:Prof David Howells
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依托单位:
Translational research in stroke
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批准号:nhmrc : 251525
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项目类别:Programs
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资助金额:$310.24万
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财政年份:2003
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负责人:Prof David Howells
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依托单位:
New dopaminergic neurons in the Parkinson's disease striatum: Establishment of phenotype, function and origin.
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批准号:nhmrc : 145758
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项目类别:NHMRC Project Grants
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资助金额:$10.43万
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财政年份:2001
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负责人:Prof David Howells
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依托单位:
New dopaminergic neurons in the Parkinson;s disease striatum: establishment of phenotype, function & origin
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批准号:nhmrc : 170211
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项目类别:NHMRC Research Fellowships
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资助金额:$45.78万
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财政年份:2001
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负责人:Prof David Howells
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依托单位:
Cellular and molecular mechanisms of axonal sprouting in the CNS
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批准号:nhmrc : 991297
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项目类别:NHMRC Project Grants
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资助金额:$24.23万
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财政年份:1999
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负责人:Prof David Howells
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依托单位:
海外基金