PROSPECTIVE MULTICENTER STUDY OF BRONCHIOLITIS ADMISSIONS: ETIOLOGY AND DISPOSIN

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 毛细支气管炎是1岁以下儿童住院的头号原因。这种常见的疾病是由感染引起的，通常是病毒。尽管这种疾病很常见，但很少有研究研究患有毛细支气管炎的儿童有患严重问题的风险，也没有研究研究婴儿出院回家何时安全。 这项研究的目的是：(1)阐明多重病原体感染的作用，并确定PCR检测在感染病原学中的作用；(2)创建高风险和低风险的临床规则，以可靠地预测需要持续正压或插管的毛细支气管炎儿童和不需要重症监护的毛细支气管炎儿童；(3)制定鼓励早期安全出院并促进以家庭为中心的护理的出院指南。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Bronchiolitis is the number one reason children younger than 1 year are hospitalized. This common disease is caused by an infection, usually a virus. Despite how common this disease is, little research has studied which children with bronchiolitis are at risk for severe problems, and no research has studied when it is safe for infants to be discharged home from the hospital. The purpose of this study is: (1) To elucidate the role of multiple pathogen infections and to determine the utility of PCR-testing for an infectious etiology; (2) To create high-risk and low-risk clinical rules to predict reliably those children with bronchiolitis who would require continuous positive airway pressure or intubation and those who would not require intensive care; and (3) To develop hospital discharge guidelines that encourage earlier but safe discharges and foster family-centered care.