Early Stage Training in the Neurosciences

描述（由申请人提供）：本申请旨在继续支持我们的“神经科学早期培训”培训基金中的9个博士前职位。这项培训补助金是为密歇根大学跨系神经科学研究生项目的预备候选人提供支持的综合计划的核心。该培训计划的前两年确保所有学生毕业时都能成为受过广泛训练的神经科学家。在第一年，学生们要修一门强化的实验课程，一门关于神经科学原理、人类神经解剖学、统计学的跨学科课程，以及一门关于研究责任和伦理的课程，此外还要进行两次实验室研究轮转。在他们的第二年，学生选修课程，参加研讨会课程，其中他们要做口头报告，完成他们的实验室轮转，并开始博士论文的初步工作。一旦学生完成了候选人前的培训，他们就会在98个不同的培训教员的实验室里进行全职博士研究。这些教师中大约有一半在基础科学部门任职，另一半在临床部门任职。在课堂和实验室，我们的学生都接触到广泛的研究课题，包括细胞和分子神经生物学，发育神经生物学和再生，临床和转化神经科学，感觉和计算神经科学，行为，情感和综合神经科学，认知神经科学和神经精神病学。在完成培训后，我们的毕业生准备处理一系列公共卫生问题，从神经退行性疾病的分子基础到精神疾病的脑回路异常。密歇根大学（University of Michigan）对其招募和培训少数族裔学生的历史感到自豪。神经科学研究生项目努力增加受训者的多样性，我们描述了我们的成就，并制定了招聘和留住代表性不足的少数群体的详细计划。我们还提出了项目评估和负责任的研究指导的详细计划。这项培训补助金对神经科学项目培训任务的成功至关重要。在过去的四年里，它为大约40%的学生提供了支持，并在培训中为大约一半的学生提供了支持。培训补助金支持各种与学员相关的活动，包括课堂实验室培训，学生参加科学会议的旅行，以及在神经科学专题讨论会和座谈会上发言。这项培训补助金是我们招募优秀学生和他们在教育上取得成功的关键。

DESCRIPTION (provided by applicant): This application seeks continuation of support for nine predoctoral positions on our training grant, 'Early Stage Training in the Neurosciences'. This training grant serves as the centerpiece in an integrated plan of support for pre-candidate students in the Interdepartmental Neuroscience Graduate Program at the University of Michigan. The first two years of this training program ensure that all students graduate as broadly trained neuroscientists. In the first year, students take an intensive lab course, an interdisciplinary course in the principles of neuroscience, human neuroanatomy, statistics, and a course in research responsibility and ethics, in addition to performing two laboratory research rotations. During their second year, students take elective courses, participate in a seminar course in which they give an oral presentation, complete their lab rotations and begin the initial work on the doctoral thesis. Once students complete pre-candidate training, they perform full-time doctoral research in the laboratory of one of 98 different training faculty members. Approximately half of these faculty members hold appointments in basic science departments, and the other half hold appointments in clinical departments. In both the classroom and laboratory, our students are exposed a broad range of research topics including Cellular and Molecular Neurobiology, Developmental Neurobiology and Regeneration, Clinical and Translational Neuroscience, Sensory and Computational Neuroscience, Behavioral, Affective, and Integrative Neuroscience, and Cognitive Neuroscience and Neuropsychiatry. Upon completion of their training, our graduates are poised to tackle a host of public health issues from the molecular basis of neurodegenerative disorders to brain circuit abnormalities in psychiatric disease. The University of Michigan is proud of its history of recruiting and training underrepresented minority students. The Neuroscience Graduate Program strives to increase the diversity of its trainees, and we describe our accomplishments and a detailed plan for recruiting and retaining underrepresented minorities. We also present detailed plans for the evaluation of the program and for instruction in the responsible conduct of research. This training grant is critical to the success of the Neuroscience Program's training mission. It has provided support for roughly 40% of the students admitted to the program in the last 4 years, and has supported roughly half of the current students in the program at one point in their training. The training grant supports a variety of trainee-related activities including classroom laboratory training, student travel to scientific conferences, and speakers at neuroscience symposia and colloquia. This training grant is key to our recruitment of outstanding students and their educational success. PUBLIC HEALTH RELEVANCE: This is an application to support Early Stage Neuroscience training for students in the University of Michigan Neuroscience Graduate Program. One of the oldest of its kind, this interdisciplinary training program is essential to for the development of the next generation of laboratory scientists capable of using state-of-the-art methodologies to understand the normal and disordered function of the brain and nervous system. Trainees in this program are poised to tackle a host of public health issues from the molecular basis of neurodegenerative disorders to the brain circuit abnormalities in psychiatric disease.