Pre-doctoral Training in Molecular and Biochemical Nutrition

描述(由申请人提供)：加州大学伯克利分校的分子和生化营养学专业为博士前研究生提供现代生化营养学领域的概念、技术和实施方面的跨学科培训，我们称之为代谢生物学。该培训计划旨在培养独立和原创的思维，并在研究、教学和专业服务方面提供学术和技能的发展。该项目旨在吸引和培养来自社会各阶层的合格学生。该计划打算获得资格 毕业生在学术界创造、指导和进行独立调查，但也认识到毕业生准备通过在政府和行业服务来为与健康有关的问题做出贡献。该计划强调对作为人类生理过程和疾病模型的人类和哺乳动物的代谢调节、营养和异物代谢和作用机制的实验室和临床前研究。通过他们在分析化学和生物化学、生物化学、分子生物学、细胞生物学、临床研究和基因组学方面的多学科专业知识，项目教员非常适合支持这一培训任务。培训任务通过参与教员的资金充足的研究计划得到加强，他们研究新陈代谢调节，重点是人类营养、营养相关疾病、营养作用机制和毒理学(如果适用)。 食源性毒物或人类故意摄入的化学品，如乙醇)。项目教职员工拥有化学、营养学、生物化学、分子生物学的博士学位，其中一些人获得了医学博士学位或医学博士/博士双学位。这些因素促进了跨学科的环境，并为合作提供了机会，以便将不同的视角和技能集中在与代谢健康相关的问题上。此外，该计划正在通过购买两个新的质谱仪和招聘教员和支持人员，将其专业知识从LC/MS/MS和GC/MS扩展到蛋白质组学和代谢组学。分子和生化营养学的跨学科培训课程在伯克利分校是独一无二的：它是唯一致力于代谢生物学的课程，即代谢生物化学、现代实验营养学和高等脊椎动物的食物毒理学。因此，该项目的目标和性质、师资、资源和环境为伯克利校区提供了一个独特的机会，可以在与常见人类疾病和疾病风险有关的代谢研究方面进行跨学科培训。

DESCRIPTION (provided by applicant): The program in Molecular and Biochemical Nutrition at the University of California, Berkeley provides interdisciplinary training for pre-doctoral candidates in the concepts, techniques, and implementation in the area of modern biochemical nutrition, which we refer to as Metabolic Biology. This training program aims to cultivate independent and original thinking, and to provide for development of scholarship and skills in research, teaching and professional service. The program has been designed and seeks to attract and nurture qualified students from all sections of society. The program intends to qualify graduates to create, direct and pursue independent investigation in academia, but also recognizes that graduates are prepared to contribute to health-related issues by serving in government and industry. The program emphasizes lab and pre-clinical investigations into metabolic regulation, and mechanisms of nutrient and xenobiotic metabolism and actions in humans, and mammals that serve as models for human physiological processes and diseases. Program faculty are well suited to support this training mission through their multidisciplinary expertise in analytical chemistry and biochemistry, biochemistry, molecular biology, cell biology, clinical studies, and genomics. The training mission is augmented through the well-funded research programs of participating faculty, who study metabolic regulation focused on human nutrition, nutrition-related diseases, mechanisms of nutrient action, and toxicology (as it applies to food-borne toxicants or chemical intentionally ingested by humans, such as ethanol). Program faculty have Ph.D. degrees in chemistry, nutrition, biochemistry, molecular biology, and several have earned MD or dual MD/Ph.D. degrees. These factors foster an interdisciplinary environment and provide opportunities for collaboration to focus different perspectives and skills on metabolic health-related issues. In addition, the program is expanding its expertise from LC/MS/MS and GC/MS, as applied to quantification of select metabolites and deuterium isotope studies, to proteomics and metabolomics through the purchase of two new mass spectrometers and hiring faculty and support personnel. The interdisciplinary training program in Molecular and Biochemical Nutrition is distinctive on the Berkeley campus: it is the only program devoted to Metabolic Biology, i.e. metabolic biochemistry, modern experimental nutrition, and food-based toxicology in higher vertebrates. Thus, the goals and nature of the program, the faculty, the resources, and the environment provide a unique opportunity on the Berkeley campus for interdisciplinary training in metabolic studies pertaining to common human diseases and disease risk.