Aged Hybrid Rat Colony

美国国家老龄研究所(NIA)资助的研究项目使用啮齿动物来模拟人类的衰老过程和与年龄相关的疾病，要求动物具有缺陷的基因并控制环境和健康状态。只有对遗传和环境变量进行细致、长期的控制，才有可能维持相关的动物模型，这些模型可能用于研究衰老过程中的许多生物和行为过程。因此，持续供应有遗传缺陷的、特征良好的近交系和杂交实验动物对衰老研究计划至关重要。本项目的目的是为南加州大学衰老研究中的研究人员建立、维护和分布一个老龄BN和F344BN FI大鼠的站立群体。

National Institute on Aging (NIA) funded research programs using rodents to model aging processes and age-related diseases in humans require animals of defmed genotype and controlled environmental and health status. Only with the meticulous, long-term control of genetic and environmental variables is it possible to maintain relevant animal models that may be used to study manyofthe biological and behavioral processes in aging. Therefore,a continuous supply of genetically defmed, well characterized inbred and hybrid laboratory animals is essential for a program of research on aging. The purpose of this project is to develop, maintain and distribute a standing colony of aged BN and F344BN FI rats for usc by investigators in studies ofaging.