A Comprehensive Patient Based Outcome Measure for Heavy Menstral Bleeding

克里斯汀·马特森博士是布朗大学妇产科助理教授， 罗得岛普罗维登斯婴儿医院。候选人的长期目标是发展一个独立的 临床研究与临床医学相结合的职业。候选人对评估感兴趣， 治疗大量月经出血，一个普遍的问题，有许多原因，包括结构性 异常、全身性疾病（如出血性疾病）和排卵功能障碍。重 经血对妇女的健康和生活质量有重大影响。"病人 必须对这种情况的“经验”进行评估，并且必须采用高质量的基于患者的结局指标， 发展。拟议的职业发展计划包括一个多学科的计划， 提供一个密切指导的以病人为导向的研究经验，与结构化的教学相结合， 调查方法和复杂数据分析课程。与一个7人咨询机构合作 委员会，候选人将制定一个有效和可靠的基于患者的结果衡量标准（"精神病学"）， 出血问卷调查"）。最先进的技术将是 探索并用于开发电子格式的"月经出血 调查表"。本研究的具体目的是：（1）确定中国传统文化的内涵和特征， 妇科医生需要一种仪器来评估大量月经出血的妇女;（2） 探讨影响女性重度抑郁症患者生活质量的生理、心理和社会因素， 月经出血;（3）制定月经出血特异性问卷，评估月经量， 出血和“条件”的具体生活质量;（4）开发创新的电子收集方法 大量月经出血患者结局指标的数据。与公众的关系 健康：月经大量出血是一个常见的问题，对生活质量有重大影响， 保健利用和费用。临床研究和临床护理的质量都受到不利影响 缺乏一个标准化的综合患者基础的结果措施，妇女报告重 经血该职业发展和研究计划旨在培养高质量的患者- 基于大量月经出血的结果测量，可用于临床护理和未来的研究。

Dr. Kristen Matteson is Assistant Professor of Obstetrics and Gynecology at Brown University/Women and Infants Hospital of Providence, Rhode Island. The candidate's long-term goal is to develop an independent career combining clinical research with clinical medicine. The candidate is interested in the evaluation and treatment of heavy menstrual bleeding, a prevalent problem that has many causes including structural abnormalities, systemic diseases (such as bleeding disorders), and ovulatory dysfunction. Heavy menstrual bleeding has a major effect on women's health and the quality of women's lives. "Patient experience" with this condition must be evaluated and a high quality patient-based outcome measure must be developed. The proposed career development plan incorporates a multi-disciplinary program designed to provide a closely mentored patient-oriented research experience in association with a structured didactic curriculum in survey methodology and complex data analyses. In collaboration with a 7 member advisory committee, the candidate will develop a valid and reliable patient-based outcome measure ("The Menstrual Bleeding Questionnaire") for heavy menstrual bleeding. The most advanced available technology will be explored and employed for the development of the electronic format of "The Menstrual Bleeding Questionnaire". The specific aims of this study are (1)To determine the content and characteristics that gynecologists would require of an instrument for evaluation of women with heavy menstrual bleeding; (2)To explore the physical, psychological, and social factors that affect the quality of life of women with heavy menstrual bleeding; (3)To develop a menstrual bleeding-specific questionnaire that assesses amount of bleeding and "condition"-specific quality of life; (4)To develop innovative electronic methods of collecting data on patient-based outcome measures for heavy menstrual bleeding. RELEVANCE TO PUBLIC HEALTH: Heavy menstrual bleeding is a common problem that has a major impact on quality of life and health care utilization and costs. The quality of both clinical research and clinical care is adversely affected by the lack of a standardized comprehensive patient base outcome measure for women reporting heavy menstrual bleeding. This career development and research plan aims to develop a high quality patient- based outcome measure for heavy menstrual bleeding that can be used in clinical care and future research.