Cell Imaging Shared Resource

先进的数字成像显微镜是糖尿病相关研究的有力工具，但设备成本和有效使用和适当维护设备的专业知识超出了大多数单个实验室的资源。我们很幸运，范德比尔特大学拥有领先的糖尿病相关成像设备之一，因此，在下一个资金周期中，DRTC将继续支持细胞成像资源共享资源，以便DRTC附属的研究人员能够以较低的价格获得其专业知识和大量设备。细胞成像共享资源的总体目标是保持全范围的现代显微镜和数字成像能力，以实现和加速研究，否则将减少数量和质量。细胞成像核心通过以下目标促进范德比尔特大学的糖尿病研究：1)获得并保持最先进的光学和EM成像技术；2)培训、协助和鼓励drtc附属研究人员将光学、EM和体内成像技术纳入他们的研究；3)开发对糖尿病研究有用的新成像技术。重要的是，该设施还将继续为糖尿病研究界开发新兴的光学和电子成像技术。从2000年到2005年，细胞成像共享资源在资源和使用方面都经历了大约500%的增长。自上次DRTC授权更新以来，细胞成像共享资源大大增加了容量和先进的成像能力。核心地区对先进的专业显微镜服务的需求依然强劲。在过去的五年中，超过75个drtc附属研究小组（包括42个现有成员）使用了细胞成像共享资源，这些研究人员使用成像资源设备和/或协助生成了100多篇同行评议的论文。这个共享资源是范德比尔特共享设施系统的一部分，该系统为核心提供了一个有效的计费系统和监督和治理。细胞成像资源共享资源将在下一个资助周期中继续提供基本服务，支持drtc附属研究人员的研究。

Advanced digital imaging microscopy is a powerful tool for diabetes-related research, but the equipment costs and expertise to efficiently use and properly maintain the equipment is beyond the resources of most individual labs. We are fortunate at Vanderbilt to have one of the leading facilities for imaging diabetes-related processes, and thus, in the next funding cycle, the DRTC will continue to support the Cell Imaging Resource Shared Resource so that DRTC-affiliated investigators will have access to its expertise and substantial facilities at a reduced rate. The overall goal of the Cell Imaging Shared Resource is to maintain the full range of modern microscopy and digital imaging capabilities to enable and accelerate research that would otherwise be reduced in quantity and quality. The Cell Imaging Core facilitates diabetes research at Vanderbilt through these objectives: 1) acquire and maintain state-of-the art optical and EM Imaging technology; 2) train, assist, and encourage DRTC-affiliated investigators to incorporate optical, EM, and in vivo imaging technologies into their research; and 3) develop new imaging technologies that will be useful for diabetes research. Importantly, this facility continues to also develop emerging optical and electron imaging techniques for the diabetes research community. Between 2000 and 2005 the Cell Imaging Shared Resource experienced approximately 500% growth in both resources and usage. Since the last DRTC grant renewal, the Cell Imaging Shared Resource has greatly increased capacity and advanced imaging capabilities. The demand for advanced, specialized microscopy service in the core remains strong. More than 75 DRTC-affiliated research groups (including 42 current members) have used the Cell Imaging Shared Resource during the last five years, and these investigators have generated more than 100 peer-reviewed papers using imaging resource equipment and/or assistance. This Shared Resource is part the Vanderbilt shared facilities system, which provides an efficient billing system and oversight and governance for the core. The Cell Imaging Resource Shared Resource will continue to provide essential services that support the research of DRTC-affiliated investigators in the next funding cycle.