Interdisciplinary Training in Rheumatic Diseases

描述（由申请人提供）：本申请要求为范德比尔特大学的流变学和免疫学部门颁发新的国家研究服务奖（T32）。近十年来，由医学系领导的范德比尔特的生物医学研究经历了前所未有的增长。这种扩张伴随着流变学部门的重建和发展。流变学部门的研究人员已经制定了非常成功的临床和基础科学研究计划，这些计划伴随着强大而多样化的临床实践。在这种环境下，由于最近的进展将分子机制转化为治疗，寻求风湿病学研究职业的学员在各个层面都有所增加。因此，一个新的培训计划将提供一个未满足的需要，在风湿性疾病的研究培训的优秀池前和博士后学员。在医学中，没有其他学科像风湿性疾病那样包含如此多的不同器官系统或具有病理生理学的多样性。因此，提出了一项风湿性疾病跨学科培训计划，该计划将为下一代研究人员提供必要的工具，以做出关键发现，并促进我们对这些复杂疾病的理解和治疗。我们的教师致力于实现这一目标，我们在培养优秀的博士研究人员和医生科学家方面的成功，没有正式的支持，证实了这一承诺。该计划将保持一个互动的发现环境，为四个关键领域的博士前和博士后学员的临床和基础研究搭建桥梁：先天和适应性免疫;血管生物学和炎症;转化和卫生服务研究;和肌肉骨骼生物学。该计划中的Preceptors具有高度互动性，并在研究小组之间保持广泛的合作努力。这种跨学科的方法将为学员提供广阔的视野，并使他们有机会对单一实验室无法解决的问题进行临床翻译。个人发展计划，正式的课程工作和学位授予途径MSCI和MPH将通过核心课程访问。该计划旨在满足那些希望将先进技术（如基因组学或蛋白质组学）应用于风湿性疾病的个人的职业目标，以及支持那些希望将这些进步转化为改善医疗保健的个人的职业生涯。本集团已设立机制，确保学员甄选及长期职业发展的平衡及多元化。优秀的内部和外部咨询委员会将确保实现这些目标。

DESCRIPTION (provided by applicant): This application requests a new Institutional National Research Service Award (T32) for the Division of Rheumatology and Immunology at Vanderbilt University. Biomedical research at Vanderbilt led by the Department of Medicine has undergone unprecedented growth in the recent decade. This expansion was accompanied by rebuilding and growth in the Rheumatology Division. Investigators in the Division of Rheumatology have generated highly successful clinical and basic science research programs and these accompany a robust and diverse clinical practice. In this environment, and as a consequence of recent advances translating molecular mechanisms into therapy, trainees seeking careers in rheumatology research have increased at all levels. Thus, a new training program will provide an unmet need for research training in rheumatic diseases for an outstanding pool of pre and postdoctoral trainees. No other discipline in medicine encompasses as many different organ systems or has the diversity of pathophysiology as do rheumatic diseases. Accordingly, a plan is proposed for Interdisciplinary Training in Rheumatic Diseases that will provide the next generation of investigators with the tools necessary to make critical discoveries and advance our understanding and treatment of these complex disorders. Our faculty is committed to this goal and our successes in producing outstanding PhD investigators and physician-scientists without formalized support confirm this commitment. The program will maintain an interactive environment of discovery that bridges both clinical and basic research for pre and postdoctoral trainees in four critical arenas: Innate and Adaptive Immunity; Vascular Biology and Inflammation; Translational and Health Services Research; and Musculoskeletal Biology. The Preceptors in the program are highly interactive and maintain extensive collaborative efforts between and among the research groups. This interdisciplinary approach will provide trainees with a broad perspective and expose them to opportunities for clinical translation of problems that cannot be solved by a single laboratory. Individual development plans, formal course work and degree granting pathways for MSCI and MPH will be accessed through a core curriculum. The program is organized to meet the career goals of individuals who want to apply advanced technologies, such as genomics or proteomics, to rheumatic diseases as well as to support the careers of individuals who want to translate these advances to improve health care. Mechanisms are in place to ensure the balance and diversity of trainee selection and long term career development. Outstanding internal and external Advisory committee's will ensure these goals are met.