Biostatistics

项目总结（见说明）：癌症研究中使用的分析方法和研究设计的多样性和复杂性日益增加，需要有组织和集中的生物统计资源，可以为阿尔伯特爱因斯坦癌症中心（AECC）的研究人员提供广泛的统计专业知识，合作和培训机会。生物统计学共享资源（BSR）由经验丰富的统计学家组成，他们在所有科学项目和许多不同方法学领域的创新研究中具有有效合作的良好记录。鉴于他们对AECC内研究活动范围的广泛了解以及与个别研究人员的众多关系，BSR人员显着增强了中心的基础设施和环境，并理想地定位于促进来自不同科学学科的成员之间的协同合作。 BSR的具体目标是： 为癌症研究的所有阶段提供最先进的统计支持，从实验设计和研究进行到数据分析和手稿准备 合作开发严格的资助申请和新的研究计划 协助临床试验方案的制定和科学审查 为癌症研究中的新技术开发创新的统计方法 提供各种统计方法的培训机会，并指导初级研究人员 通过参与科学和行政委员会以及与其他共享资源的互动，加强AECC基础设施，促进跨学科合作。实现这些目标的总体目标是一个强大的，全面和成本-为AECC研究人员提供有效的统计支持系统，有助于促进我们对不同类型癌症的科学理解，并在癌症的发展方面取得更大进展。改进预防检测和治疗战略。

PROJECT SUMMARY (See instructions): The increasing variety and complexity of analytic approaches and study designs utilized in cancer research necessitate the availability of an organized and centralized biostatistics resource that can offer a wide range of statistical expertise, collaboration, and training opportunities to investigators in the Albert Einstein Cancer Center (AECC). The Biostatistics Shared Resource (BSR) is staffed by experienced statisticians with proven track records of effective collaboration across all scientific programs and innovative research in many different methodologic areas. Given their broad knowledge of the scope of research activities within the AECC and numerous relationships with individual investigators, BSR personnel significantly enhance the Center infrastructure and environment and are ideally positioned to foster synergistic collaborations among members from different scientific disciplines. The specific objectives of the BSR are: ¿ To provide state-of-the-art statistical support on all phases of cancer research, from experimental design and study conduct to data analysis and manuscript preparation ¿ To collaborate on the development of methodologically rigorous grant applications and new research initiatives ¿ To assist with the development and scientific review of clinical trial protocols ¿ To develop innovative statistical approaches for new technologies in cancer research ¿ To offer a variety of training opportunities in statistical methods and to mentor junior investigators ¿ To enhance the AECC infrastructure and foster interdisciplinary collaborations via participation on scientific and administrative committees and interactions with other shared resources The overall goal in accomplishing these objectives is a robust, comprehensive and cost-effective system of statistical support for AECC investigators that contributes significantly to advancing our scientific understanding of different types of cancer and greater progress in the development of improved prevention detection, and treatment strategies.