Biomedical Explorations: Bench to Bedside Phase II

描述(由申请人提供)：目前佛罗里达州和美国国立卫生研究院在翻译研究方面的倡议要求今天的学生理解并在学术上为从基础研究到适销对路的药品、诊断和设备等领域越来越多的研究、临床和技术职位做好准备。然而，很少有高中教师意识到或获得关于迅速发展的生物医学科学内容、技术和职业的信息。为了解决这一未得到满足的需求，我们创建了生物医学探索：从工作台到床边项目，该项目建议建立和扩大合作伙伴关系，以(1)将跨学科生物医学科学的研究人员与高中教师联系起来，(2)促进对生物科学职业的兴趣和准备。目前，在三年周期的第二年结束时，阶段已经成功地产生了合作，弥合了从尖端研究实验室到佛罗里达州各地的高中科学教师，再到这些社区中有才华的年轻学生的差距。 我们的新提议，生物医学探索：从板凳到床边阶段II，建立在第一阶段建立的科学和教育伙伴关系的基础上，通过一个创新的项目，将暑期学院的经验整合到学年的课堂行动中。在研究所期间，真实的基础科学、临床和应用研究环境中的实验序列展示了当前的科学内容、教学方法、多样化的职业选择以及从工作台到床边连续体的概念和技术相互关系。在本学年，行动研究、资源、演讲、课堂结果回顾和持续专业发展的激励措施为教师提供持续的支持和鼓励。 这一建议将第一阶段的经验与与研究实习有关的新课程结合起来，向学生传达生物医学背景下的转化研究和药物开发的原则。我们预计，这些课程的开发将进一步帮助教师将科学过程、现实世界技能、热情或生物科学职业过渡到农村和经济困难环境中的学校。

DESCRIPTION (provided by applicant): Current Florida and NIH initiatives in translational research require that today's students understand, and are academically prepared for, the research, clinical and technical positions increasingly available in the continuum from basic research to marketable medicines, diagnostics and devices. However, few high school teachers have awareness or access to information about rapidly developing biomedical science content, technologies, and careers. To address this unmet need, we created the Biomedical Explorations: Bench to Bedside project, which proposes to create and expand partnerships that (1) connect researchers in interdisciplinary biomedical sciences with teachers in high schools and (2) promote interest in and preparation for bioscience careers. Currently at the end of year 2 in a 3 year cycle, Phase has had success in generating collaborations that bridge the gaps from cutting edge research labs to high school science teachers across Florida, and on to talented young students in those communities. Our new proposal, Biomedical Explorations: Bench to Bedside Phase II, builds on the science and education partnerships created in Phase I via an innovative program that integrates experiences from a summer Institute into classroom action during the school year. During the Institute, an experimental sequence in authentic basic science, clinical and applied research environments illustrate current scientific content, pedagogical methods, diverse career options, and conceptual and technological interrelationships within the bench to bedside continuum. During the school year, action research, resources, presentations, review of classroom outcomes, and incentives for ongoing professional development provide teachers with continuing support and encouragement. This proposal integrates the Phase I experience with new curricula related to research internships which convey to students the principles of translational research and drug development in the context of biomedicine. We anticipate that development of these curricula will further aid teachers in transitioning scientific processes, real-world skills, and enthusiasm or bioscience careers to schools in rural and economically disadvantaged settings.