Core A

行政核心A将促进计划成员之间的互动，并为项目和核心提供生物统计支持。POI成员之间的沟通对于该计划的成功至关重要。有效的沟通将促进项目之间的协作和协同，并加快发现的步伐。对科学进展和核心评价的定期内部和外部审查将促进研究的卓越，并确保向项目提供最高质量的服务。应用适当的统计工具对于严格评估假设和改进实验设计是必不可少的。行政核心的职能包括通过支持弗吉尼亚大学和科罗拉多大学之间的基于网络的交流来促进计划内的沟通和合作，组织定期的科学会议，以及为项目负责人和核心主任提供行政支持。核心还将监督对项目和核心的科学质量和财政管理的审查。核心的另一项关键活动是为方案提供统计支持和指导。这包括协助设计和分析体外和体内研究、开发和应用新的统计方法以支持新的计划目标，以及提供统计方法方面的培训。

The Administrative Core A will facilitate interactions between Program members and provide biostatistical support for Projects and Cores. Communication between POI members is critical for success of the Program. Effective communication will promote collaboration and synergy between projects, and accelerate the pace of discovery. Regular internal and external review of scientific progress and evaluation of cores will promote research excellence and ensure that projects are provided with the highest quality services. Application of appropriate statistical tools is essential for rigorous evaluation of hypotheses and for improving experiment design. Functions ofthe Administrative Core include promoting communication and collaboration within the Program by supporting web-based communication between the University of Virginia and the University of Colorado, organizing regular scientific meetings, and providing administrative support to Project Leaders and Core Directors. The Core will also oversee the review of scientific quality and fiscal management of the Projects and Cores. Another key activity of the Core is to provide statistical support and instruction for the Program. This involves assisting in the design and analysis of in vitro and in vivo studies, development and application of novel statistical methodologies in support of emerging Program objectives, and provision of training in statistical methods.