Basic Science

基础科学核心的总体目标是通过提供最新技术来加强艾滋病毒/艾滋病研究 以具有成本效益的方式发展科学技术。我们将：1)提供基础科学服务， 包括与分子生物学、生物化学、免疫学和病毒学相关的学科。分子生物学 核心的生化成分将主要位于UIC的研究资源中心， 结构生物学中心和核心负责人迈克尔·卡弗里的实验室。免疫学 核心部件将主要位于D-CFAR艾伦·兰迪实验室的RUMC 导演。核心的病毒学部分将主要设在位于詹姆斯实验室的RUMC 核心的联席主任布雷默说。2)为毕业时使用这些技术提供培训和建议 学生、博士后助理和主要研究人员。3)鼓励互动和协作 在核心用户之间。每月举办研讨会，讲解可用于 基础科学核心将得到赞助。将鼓励所有D-CFAR成员及其实验室 出席。4)将D-CFAR的基础科学核心发展成为CFAR的基础科学核心。最基本的 Science Core将努力通过鼓励对所提供服务的反馈来适应D-CFAR成员的需求， 服务质量、服务成本和建议的新服务。将努力扩大数量 用户。基础科学核心将由迈克尔·卡弗里博士执导，詹姆斯博士联合执导 来自RUMC的布雷默。卡弗里博士目前是伦敦大学伯克利分校 UIC生物化学和分子遗传学。他的研究兴趣集中在结构和功能上 艾滋病毒和艾滋病相关蛋白的性质。他在各种各样的实验技术方面都有专业知识 对艾滋病毒/艾滋病研究很重要，包括：分子生物学、细胞生物学、病毒学、蛋白质 纯化、蛋白质表征、药物发现和结构生物学。布雷默博士是一位终身教授 免疫学与微生物学系教授、病毒学质量学主任 RUMC的保证实验室。他的实验室在临床技术方面有丰富的经验。 病毒学。

The overall objective of the Basic Science Core is to enhance HIV/AIDS research by providing state of the art sic science technologies in a cost efficient manner. We will: 1) Provide basic science services, which include those related to molecular biology, biochemistry, immunology and virology. The molecular biology and biochemistry components of the core will be primarily located at UIC in the Research Resources Center, the Center for Structural Biology and the laboratory of the core's director, Michael Caffrey. The immunology component of the core will be primarily located at RUMC in the laboratory of Alan Landay, the D-CFAR Director. The virology component of the core will be primarily located at RUMC in the laboratory of James Bremer, the co-Director of the core. 2) Provide training and advice for the use of these techniques to graduate students, post doctoral associates, and principal investigators. 3) Encourage interaction and collaboration between users of the core. Monthly workshops on the theory and practice of the techniques available in the Basic Science Core will be sponsored. All D-CFAR members and their laboratories will be encouraged to attend. 4) Develop the Basic Science Core of the D-CFAR into a Basic Science Core of a CFAR. The Basic Science Core will strive to adapt to D-CFAR members needs by encouraging feedback on services provided, quality of service, cost of service, and suggested new services. Efforts will be made to expand the number of users. The Basic Science Core will be directed by Dr. Michael Caffrey and will be co-directed by Dr. James Bremer from RUMC. Dr. Caffrey is currently a tenured Associate Professor in the Department of Biochemistry and Molecular Genetics at UIC. His research interests are focused on the structure and function properties of HIV and AIDS-related proteins. He has expertise in wide variety of experimental techniques that are important for HIV/AIDS research including: molecular biology, cell biology, virology, protein purification, protein characterization, drug discovery, and structural biology. Dr. Bremer is a tenured Professor in the Department of Immunology and Microbiology and Director of the Virology Quality Assurance Laboratory at RUMC. His laboratory has extensive experience in the techniques of clinical virology.