Interactions between diet, microbiome, genetics and epigentics in determining risk for adenomatous polyps

生活在肠道中的细菌与宿主细胞相互作用，被认为有助于引起或预防包括肠癌在内的疾病。我们知道饮食可以改变这些细菌的数量，但我们仍然不完全了解它们是如何与宿主细胞相互作用的。我们个人基因的差异经常被包括在肠道细菌、健康和疾病的研究中。这个项目旨在考虑味觉基因在改变细菌和身体反应中的作用。

The bacteria that live in the gut interact with the hosts cells and are thought to contribute to causing or preventing diseases, including bowel cancer. We know that diet can change these bacteria populations, but we still do not fully understand how they interact with host cells. The differences in our personal genes are often included in studies of gut bacteria and health and disease. This project aims to consider the role of genes for taste in changing the bacteria and the body’s responses.