Clinical Characterization and Biorepository Core

临床表征和生物库核心（CCBC）为ORDRCC研究人员提供了独特的患者收集和新的招聘机会，以帮助他们的风湿病研究项目，并帮助促进他们的职业发展。该核心为面向患者的研究培训、患者/对照识别和招募以及样本处理提供了一个集中的过程，并提供了大量患者和对照样本的访问，这些样本具有相关的临床、人口统计学、治疗和疾病活动测量。基于最近资金的一些变化，临床表征和生物储库核心将包括以前的ORDRCC样本采购和管理核心（SPMC），以及历史上狼疮家族登记处和储库的样本和数据，以促进ORDRCC研究者和初级研究者的临床调查。OMRF SPMC是在ORDRCC的资助下建立的，并支持了37名ORDRCC初级调查员（来自俄克拉何马州内外，从南卡罗莱纳到阿拉斯加，从芝加哥到加利福尼亚）和19名ORDRCC中心调查员的项目。临床表征和生物库核心的目标是：

The Clinical Characterization and Biorepository Core (CCBC) provides ORDRCC investigators with access to unique patient collections and new recruitment opportunities to aid their rheumatic disease research programs and to help facilitate their career development. This Core provides a centralized process for patient-oriented research training, patient/control identification and recruitment, and sample processing, as well as access to large collections of patient and control samples with associated clinical, demographic, therapeutic and disease activity measures. Based upon some recent changes in funding, the Clinical Characterization and Biorepository Core will encompass the previous ORDRCC Sample Procurement and Management Core (SPMC), along with samples and data from the historical Lupus Family Registry and Repository, to facilitate the clinical investigation of ORDRCC investigators and junior investigators. The OMRF SPMC was established with the funding of the ORDRCC, and has supported projects from 37 Junior ORDRCC Investigators (both from inside and outside Oklahoma, spanning from South Carolina to Alaska and from Chicago to California) and 19 ORDRCC Center Investigators. The goals of the Clinical Characterization and Biorepository Core are to: 1) Facilitate human subject recruitment, re-contact, consent and compliance. The CCBC ensures that human subject recruitment, clinical assessments and sample donation procedures meet rigorous standards of good clinical practice. By performing services in informed consent, regulatory reporting, oversight of the welfare of clinical study participants, and provision of expert clinical assessments using validated disease activity instruments, the CCBC supports and expands the research opportunities of all ORDRCC investigators. 2) Process and code samples provided to ORDRCC investigators. The CCBC ensures timely, protocol-driven processing, coding, storage and tracking of human biologic samples. 3) Provide samples and associated clinical data to ORDRCC research projects. Extensive clinical, demographic, disease activity and disease damage data exists on patients enrolled with systemic rheumatic diseases. The CCBC will make ORDRCC investigators aware of various patient and control clinical information and associated samples, which will be useful for their various projects. 4) Train ORDRCC junior investigators in human subject research. The ORDRCC helps ensure appropriate HIPAA and human subjects training of all ORDRCC personnel and training of personnel in use of the central OMRF Autoimmune Disease Institute data system.