Musculoskeletal Research Training Program

描述（由申请人提供）：本肌肉骨骼研究培训计划的目标是为马约诊所的博士后研究员，研究生和医学生提供多学科研究机会，并培养他们成为生物医学研究的未来领导者。骨关节炎、骨质疏松症、背痛和骨折等肌肉骨骼疾病是患者就医的最常见原因，因此对生活质量和经济产生重大影响。肌肉骨骼组织和关节的修复、再生或复原需要复杂且相互关联的生物力学、生物学和生理学过程的知识。因此，该计划旨在培养未来的生物学家，工程师和医生/外科医生，通过在最先进的医疗和研究中心的环境中提供出色的研究和教育机会来解决骨科和肌肉骨骼问题。19名教师谁是骨科，内分泌学，传染病和神经肌肉控制的基础，转化和临床研究的领导者将通过指导研究项目和及时的主题小组讨论指导学员。新学员还可利用同侪指导制度，从成功获得独立研究金的老学员那里获得建议和咨询。博士后研究员（每年4名）和研究生（每年2名）将参与多年项目，并接受赠款写作和职业发展方面的培训。他们将提交独立奖学金申请，并参加一系列计划活动，包括但不限于期刊俱乐部，研讨会，网络研讨会，国家科学会议和负责任的研究培训。医学生（每年2名）来自美国及其领土（即，波多黎各）将在培训计划中度过两到三个月，并在导师的指导下完成一个确定的研究项目，并参加教学教育活动。这个混合的肌肉骨骼研究培训计划重视来自不同教育和社会背景的个人，并从他们解决复杂医疗问题和减轻肌肉骨骼疾病对患者，他们的家庭和我们的社会的负担的独特视角中受益。

DESCRIPTION (provided by applicant): The goals of this Musculoskeletal Research Training Program are to provide multidisciplinary research opportunities for postdoctoral fellows, graduate students, and medical students at Mayo Clinic and to train them to be future leaders of biomedical research. Musculoskeletal ailments such as osteoarthritis, osteoporosis, back pain, and fractures are some of the most common reasons why patients visit a doctor and as such have significant effects on quality of life, as well as our economy. The repair, regeneration, or rejuvenation of musculoskeletal tissues and joints requires knowledge of complex and interconnected biomechanical, biological, and physiological processes. Thus, this program aims to train future biologists, engineers, and physicians/surgeons to solve orthopedic and musculoskeletal problems by providing outstanding research and educational opportunities within the setting of a state-of-the-art medical and research center. Nineteen faculty members who are leaders in basic, translational, and clinical research of orthopedics, endocrinology, infectious disease, and neuromuscular control will mentor trainees by directing research projects and group discussions on timely topics. A peer-mentoring system is also available for new trainees to receive advice and counseling from past trainees who successfully obtained independent fellowships. Postdoctoral fellows (4 per year) and graduate students (2 per year) will engage in multiyear projects and receive training in grant writing and career development. They will be expected to submit applications for independent fellowships and to participate if a full array of programmatic activities, including but not limited to journal clubs, seminars, webinars, national scientific meetings, and training in the responsible conduct of research. Medical students (2 per year) from fully accredited medical schools in the United States and its territories (i.e., Puerto Rico) will spend two to three months in the training program and be expected complete a defined research project under the guidance of a mentor(s) and to participate in didactic educational activities. This blended musculoskeletal research training program values individuals from diverse educational and societal backgrounds and benefits from the unique perspectives they bring to solving complex medical problems and reducing the burden of musculoskeletal diseases on patients, their families and our society.