Morehouse Cardiovascular Research Center of Excellence

描述(由申请人提供)：种族/民族健康差距的双刃剑问题和少数族裔科学家代表性不足是生物医学领域面临的两个最紧迫的挑战。少数群体服务机构(MSI)未得到充分利用 作为这些恼人问题的解决方案的一部分。莫尔豪斯医学院(MSM)的核心使命是通过教育比例较高的未被充分代表的少数族裔学生来扩大国家生物医学劳动力的多样性，并为他们成为科学领袖做好准备。男男性接触者的社会使命致力于通过“服务于服务不足的人”来解决健康不平等问题。MSM作为MSI具有独特的定位，可以利用这一PSO奖励机制建立NHLBI卓越研究中心，该中心在前沿发现科学、少数族裔健康研究和培训代表不足的少数族裔研究人员方面卓越，以成为下一代科学领袖。PSO计划的长期目标与MSM的使命很好地结合在一起，这产生了行政领导层强有力的机构承诺。我们的方法寻求通过将粒子群计划的资源集中在我们的三大资产上--我们的教师、我们的研究基础设施和我们未来的科学家--来增强实力。因此，PSO计划的三个主要目标是：1)留住已向CVRI朗诵的“新调查人员”并促进其职业发展；2)不断加强我们的共享资源；以及3)进一步改善我们为代表不足的少数族裔学生提供的研究培训环境。这些目标将通过追求以下具体目标来实现：目标一：指导和培养一大批有才华的研究人员，他们将成为独立研究计划和跨学科、协作研究团队的领导者。目标二：建立支持前沿心血管科学的使能技术和共享使用的研究基础设施。目标三：通过维持有利于培养和培养少数族裔学生成为主要研究人员的充满活力的智力环境，扩大生物医学研究界的种族/民族多样性。目标四：开发创新的跨学科研究计划，整合基础、翻译、临床和人口科学方法，以解决心血管健康方面的种族/民族差异。 相关性：生物医学研究界面临的两个最严重的问题是：1)与种族/民族有关的健康差距问题；2)缺乏少数群体科学家。一个关键的解决办法是在为少数群体服务的机构建立研究培训能力，这些机构为很大比例的少数群体学生提供教育，并侧重于创新的转化研究，以增进少数群体社区的健康。

DESCRIPTION (provided by applicant): The dual-edged problem of racial/ethnic disparities in health and the under-representation of minority scientists are two of the most compelling challenges facing the field of biomedicine. Minority-Serving Institutions (MSIs) are under-utilized as part of the solution to these vexing problems. The core mission of the Morehouse School of Medicine (MSM) is to expand the diversity of the nation's biomedical workforce by educating a high proportion of under-represented minority students and prepare them to be scientific leaders. MSM's social mission is dedicated to addressing health inequities by 'serving the underserved'. MSM is uniquely positioned as a MSI to utilize this PSO award mechanism to establish a NHLBI Research Center of Excellence that is preeminent in leading-edge discovery science, minority health research and training under-represented minority investigators to emerge as the next generation of scientific leaders. The long-term goals of the PSO Program are well aligned with MSM's mission and this has engendered the strong institutional commitment of the executive leadership. Our approach seeks to build strength upon strength by focusing the PSO program resources on our three major assets ~ our faculty, our research infrastructure and our future scientists. Accordingly, the three major objectives of this PSO program are; 1) the retention and career development of 'new investigators' that have already been recited to the CVRI, 2) the ongoing enhancement of our shared-use resources, and 3) the further refinement of our research training environment for under-represented minority students. These objectives will be achieved by pursuing the following specific aims: Aim I: To mentor and develop a critical mass of talented investigators that emerge as leaders of independent research programs and cross-disciplinary, collaborative research teams. Aim II: To establish enabling technologies and a shared-use research infrastructure that supports leading- edge cardiovascular science. Aim III: To expand the racial/ethnic diversity of the biomedical research community by sustaining a vibrant intellectual environment conducive to training and nurturing the development of minority students into leading investigators. Aim IV: To develop innovative, cross-disciplinary research programs that integrate basic, translational, clinical and population science approaches to address racial/ethnic disparities in cardiovascular health. RELEVANCE: Two of the most critical problems facing the biomedical research community are: 1) the problem of health disparities related to race/ethnicity and 2) the lack of minority scientiss. A key solution is to build research training capacity at minority-serving institutions that educatea large proportion of minority students and are focused on innovative translational research that enhances the health of minority communities.