2012 ASN Advances in Research Conference: Auto and Alloimmunity

描述（由申请人提供）：美国肾脏病学会（American Society of Nephrology）年会是世界上肾脏领域临床和基础科学家的最大聚会。在每年的年会之前，肾脏病研究所都会举办一个密集的基础科学研讨会，其主题由肾脏病研究所的基础科学委员会选择，反映了一个影响肾脏领域的重大进展的研究领域。该会议旨在促进新的合作，并促进新技术在肾脏研究中的应用。将于2012年10月30日至31日在圣地亚哥举行的2012年研究进展会议的主题是“自身免疫和同种异体免疫”。会议将有31名资深研究人员参加，其中许多人来自肾脏病学领域以外，他们将就基础免疫学、自身免疫和同种免疫的各个方面发表演讲。演讲者将讨论的具体科学主题包括自我和非自我识别和耐受机制，先天和适应性系统在自身免疫和同种免疫中的作用，自身抗原和自身抗体在自身免疫性肾病中的作用，免疫反应的调节以及这些领域基础知识的临床应用。所讨论的主题具有高度的临床相关性，因为自身免疫性肾病是肾衰竭的主要原因，肾移植是器官移植的主要形式和终末期肾病的最佳治疗。在这次会议上，免疫学委员会成员和其他感兴趣的与会者将有机会与基础免疫学，自身免疫学和移植免疫学的世界领导者进行互动，并将接触到最先进的研究。本补助金申请的目的是为初级教师，博士后研究员和研究生旅行奖励申请资金，以便成员可以在2012年圣地亚哥年会之前参加本次会议。

DESCRIPTION (provided by applicant): The annual meeting of the American Society of Nephrology (ASN) is the largest gathering in the world of clinical and basic scientists working in the renal field. Prior to each annual meeting the ASN sponsors an intensive basic science symposium whose topic, selected by the ASN's Basic Science Committee, reflects an area of investigation with major advances that impact the renal field. The conference is intended to foster new collaborations and promote applications of new technologies for studying the kidney. The 2012 Advances in Research Conference to be held in San Diego on October 30-31, 2012 is entitled "Autoimmunity and Alloimmunity". The conference will feature 31 established investigators, many of them from outside the field of nephrology, who will speak on diverse aspects of fundamental immunology, autoimmunity, and alloimmunity. The specific scientific themes of the meeting to be addressed by the Speakers include self and non-self-recognition and mechanisms of tolerance, role of the innate and adaptive systems in autoimmunity and alloimmunity, role of auto-antigens and autoantibodies in autoimmune renal disease, regulation of the immune response, and clinical application of basic knowledge in these areas. The topics discussed are of high clinical relevance as autoimmune renal disease is a leading cause of kidney failure and renal transplantation is the leading form of organ transplantation and the optimal therapy for endstage renal disease. At this conference, ASN members and other interested participants will have the chance to interact with world leaders in fundamental immunology, autoimmunity, and transplantation immunology and will be exposed to state-of-the-art research. The purpose of this grant application is to request funds for junior faculty, postdoctoral fellow, and graduate student travel awards so that members can attend this conference prior to the 2012 ASN annual meeting in San Diego.