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中文摘要
翻译
物理化学纳米特征化芯 。这个核心的作用将是提供必要的物理化学表征 在所有CCNE项目中制备的纳米修复材料,如聚合物纳米颗粒、脂质纳米颗粒、树枝状大分子和自组装纳米系统。一系列复杂的显微镜、光谱和分析工具可用于研究这些纳米修复材料的尺寸、尺寸分布、稳定性、表面电荷和药物加载/释放。这一核心带来了纳米技术的基础科学和工程方面的专业知识,这对于理解这些纳米修复的基本特性至关重要。来自这个核心的反馈将帮助参与这些项目的科学家优化这些纳米修复材料,以便成功地用于癌症治疗。该核心还将与纳米表征实验室(NCL)并行工作,以促进CCNE将基础研究转化为纳米药物的工业化生产的总体使命。
英文摘要
PHYSICO-CHEIVIICAL NANOCHARACTERIZATION CORE . The role of this core will be to provide the necessary physico-chemical characterization of nanopreparations such as polymeric nanoparticles, lipid nanoparticles, dendrimers, and selfassembling nanosystems prepared in all the CCNE projects. An array of sophisticated microscopic, spectroscopic and analytical tools are available to study the size, size distribution, stability, surface charge, and drug loading/release from these nanopreparations. This core brings expertise in the basic science and engineering aspects of nanotechnology that is essential to understand the fundamental properties of these nanopreparations. Feedback from this core will help the scientists engaged in these projects to optimize these nanopreparations for successful use in cancer therapy. This core will also work in parallel with Nano Characterization Laboratory (NCL) to facilitate the overall mission of this CCNE to translate basic research to industrial production of nanomedicines.
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Drug-eluting Brachytherapy Implants for Chemo-radiation Therapy
  • 批准号:
    9908977
  • 项目类别:
  • 资助金额:
    $100.72万
  • 财政年份:
    2017
  • 负责人:
    SRINIVAS SRIDHAR
  • 依托单位:
Drug-eluting Brachytherapy Implants for Chemo-radiation Therapy
  • 批准号:
    10017919
  • 项目类别:
  • 资助金额:
    $99.28万
  • 财政年份:
    2017
  • 负责人:
    SRINIVAS SRIDHAR
  • 依托单位:
Drug-eluting Brachytherapy Implants for Chemo-radiation Therapy
  • 批准号:
    9466175
  • 项目类别:
  • 资助金额:
    $22.5万
  • 财政年份:
    2017
  • 负责人:
    SRINIVAS SRIDHAR
  • 依托单位:
CaNCURE: Cancer Nanomedicine Co-ops For Undergraduate Research Experiences
  • 批准号:
    9081554
  • 项目类别:
  • 资助金额:
    $22.6万
  • 财政年份:
    2014
  • 负责人:
    SRINIVAS SRIDHAR
  • 依托单位:
海外基金