Pediatric Dermatology Research Alliance (PeDRA) Annual Conference

 描述(申请人提供)：儿科皮肤科医生照顾患有一系列罕见和常见疾病的儿童，例如需要系统治疗的严重炎症性皮肤病，毁容的血管胎记，以及可能危及生命的遗传性皮肤病和皮肤肿瘤。对于这些严重的疾病，FDA批准的治疗方法很少，非常需要标准化的治疗方案和方法来衡量反应。儿科皮肤病研究联盟(PEDRA)就是为了解决这一治疗不足而成立的。佩德拉的愿景是创建和维持合作研究网络，开展精心设计的高质量多中心研究，以更好地了解、预防、治疗和治愈儿童皮肤病。佩德拉年会是实现这些目标的核心，包括说教讲座、由研究方法专家领导的互动讨论、小组和海报会议，以及以疾病为重点的小组会议。其具体目标是：1)为新的和现有的Pedra研究人员提供必要的知识库和基础设施，以便对儿科皮肤病进行高质量的多中心研究；2)确定并优先考虑临床的需求和儿科皮肤科五个特定领域的治疗机会：炎症性皮肤病、胎记、遗传性皮肤病、早产儿和足月新生儿皮肤、皮肤恶性肿瘤和前驱病变；以及3)通过促进基础科学家、内科研究人员和临床医生之间的想法交流和对话，增加转化研究倡议和创新治疗方法的机会。

 DESCRIPTION (provided by applicant): Pediatric dermatologists care for children with a broad range of rare and common disorders, such as severe inflammatory skin diseases that require systemic therapy, disfiguring vascular birthmarks, and genetic skin disorders and cutaneous tumors that can be life-endangering. There is a paucity of FDA-approved therapies for these severe conditions and a great need for standardized treatment protocols and methods to measure response. The Pediatric Dermatology Research Alliance (PeDRA) was established to address this therapeutic shortfall. PeDRA's vision is to create and sustain collaborative research networks that conduct well- designed, high-quality multicenter studies to better understand, prevent, treat and cure dermatologic diseases in children. The PeDRA Annual Conference is central to achieving these goals and includes didactic lectures, interactive discussions led by experts in research methodology, panel and poster sessions, and disease-focused small-group meetings. The specific aims are: 1) To provide new and established PeDRA investigators with an essential knowledge base and infrastructure to conduct high-quality multicenter research in pediatric skin disorders; 2) To identify and prioritize the clinica needs and therapeutic opportunities in five specific areas of pediatric dermatology: inflammatory skin diseases, birthmarks, genetic skin disorders, premature and term neonatal skin, and cutaneous malignancies and precursor lesions; and 3) To enhance opportunities for translational research initiatives and innovative therapeutic approaches by facilitating idea-sharing and dialogue between basic scientists, physician investigators, and clinicians.