Measurement of Quality of Life and Perceived Disease Impact on Quality of Life in

描述（由申请人提供）：现有哮喘相关生活质量（QoL）量表未直接评估QoL或哮喘对QoL的感知影响。本研究的目的是评价一种新的测量成人哮喘患者感知的负面影响的方法--哮喘对生活质量影响量表（A-IQOLS）的心理测量学特性（信度、同时和纵向效度以及对哮喘状态变化的反应性），并将其特性与当前生活质量测量方法--Flanagan生活质量量表（QOLS）的特性进行比较。我们假设A-IQOLS所代表的方法将被证明上级QOLS作为临床研究的结果指标。这项研究可以填补目前可用工具的重大空白，从而对哮喘临床治疗有益。 研究，并可能在其他疾病领域以患者为中心的结果的测量。

DESCRIPTION (provided by applicant): Existing asthma-related quality of life (QoL) scales do not directly assess QoL or the perceived impact of asth- ma on QoL. The purpose of this study is to evaluate the psychometric properties (reliability, concurrent and longitudinal validity, and responsiveness to change in asthma status) of a new measure of the patient- perceived negative effects of asthma in adults, the Asthma Impact on Quality of Life Scale (A-IQOLS), and to compare its properties with those of a measure of current QoL, the Flanagan Quality of Life Scale (QOLS). We hypothesize that the approach represented by the A-IQOLS will prove superior to that of the QOLS as an out- come measure for clinical research. This research can fill a significant gap in the currently available tools, with consequent benefit to asthma clinical research and, potentially, measurement of patient-centered outcomes in other disease areas.