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中文摘要
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科学核心将是一个共享的研究资源,为研究人员提供服务,专业知识和设备,以支持,加强和整合动物和人类研究,从而促进中心的共同目标。科学核心将巩固和标准化产前酒精暴露程序和小鼠群体管理。除了减少研究费用外,这将使调查人员能够查询他们的调查结果与其他研究组成部分所获结果之间的关系,从而促进研究组成部分的整合。科学核心还将管理小鼠行为设施,该设施将用于几个中心组成部分中提出的研究。科学核心还将通过协助研究人员实施新的行为和酒精暴露范例来支持新研究方向的发展。科学核心将为所有研究组成部分提供统计支持,并将通过提供正式的月度论坛,用于数据展示和潜在合作的讨论,促进所有中心研究者之间的互动。这些每月的协同会议将旨在整合PSO的组成部分,并促进转化研究工作的发展。最后,除了向中心的各个研究部门提供服务外,科学核心将在有限的基础上支持与中心主题有关的独立资助的研究项目赠款,从而帮助扩大中心研究活动的广度。
英文摘要
The Scientific Core will be a shared, research resource that provides investigators with services, expertise and equipment that will support, enhance and integrate the'^animal and human studies, thereby promoting the common goals of the Center. The Scientific Core will consolidate and standardize prenatal alcohol exposure procedures and mouse colony management. In addition to reducing research costs, this will allow investigators to query relationships between their findings and those obtained in other research components and, thus, facilitate integration of the research components. The Scientific Core will also manage the mouse behavioral facility that will be used for studies proposed in several Center components. The Scientific Core will also support the development of new research directions by assisting investigators with implementation of novel, behavioral and alcohol exposure paradigms. The Scientific Core v/ill provide statistical support for all of the research components, and will promote interaction among all Center investigators by providing a formal monthly forum for data presentation and discussion of potential collaborations. These monthly Synergy Meetings will aim to integrate the PSO components and foster the development of translational research efforts. Finally, in addition to providing services to the individual research components of the Center, the Scientific Core will, on a limited basis, support independently funded research project grants related to the Center's theme, thereby helping to expand the breadth of the Center's research activities.
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Scientific Core
Impact of Prenatal Alcohol Exposure on Receptor Targeting and Functioning
Impact of Prenatal Alcohol Exposure on Receptor Targeting and Functioning
Protein-protein interaction domains: targets for neuropharmacologic intervention
  • 批准号:
    7019278
  • 项目类别:
  • 资助金额:
    $16.7万
  • 财政年份:
    2006
  • 负责人:
    Kevin K. Caldwell
  • 依托单位:
海外基金