Sedentary Behavior Characteristics, Sedentary Profiles, and Subsequent Functional Loss

 描述（由申请人提供）：本拟议项目的目的是识别和描述与功能不良风险升高的老年人随后功能丧失相关的特定久坐特征和久坐特征。该提案响应了PA-13-237关于确定可改变的风险因素，如久坐不动的生活方式。我们将对骨关节炎倡议（OAI）数据库进行二次数据分析，该数据库是对膝关节骨关节炎或膝关节骨关节炎风险因素（例如，肥胖、膝关节疼痛）。建议减少久坐行为，作为预防不良健康结果的策略。然而，不知道久坐行为的哪些方面是有问题的。OAI的公共数据提供了客观的身体活动评估，从加速度计监测和纵向临床评估，以追求以下目标：目标1。描述日常久坐行为特征描述日常久坐行为特征的分布：1）总久坐时间，2）久坐发作（会话）的最大持续时间，3）久坐休息频率，以及4）久坐休息期间的身体活动持续时间/强度水平。目标2：识别不同的久坐特征识别不同的基线久坐特征的存在（即，目标1）中的久坐行为特征的组合，并评估其分布。潜在特征分析将用于识别久坐特征。目标3。久坐行为特征和特征与功能丧失的相关性评价久坐行为特征（目标1）和久坐特征（目标2）与第2年功能丧失的相关性的相对强度。这项研究的结果将扩大对久坐行为特征、久坐特征及其与随后功能丧失的关联的理解，以指导制定更有效的干预措施，维持老年人的功能和独立性。

 DESCRIPTION (provided by applicant): The objective of this proposed project is to identify and describe specific sedentary characteristics and sedentary profiles associated with subsequent functional loss in older adults at elevated risk for poor function. The proposal responds to PA-13-237 regarding the identification of modifiable risk factors such as sedentary lifestyles. We will conduct a secondary data analysis of the Osteoarthritis Initiative (OAI) database, which is a cost effective use of publicly available data on a sample of older adults at elevated risk for functional loss due to knee osteoarthritis or knee osteoarthritis risk factors (eg., obesity, knee pain). Reducing sedentary behavior is recommended as a strategy to prevent poor health outcomes. However, it is not known which aspects of sedentary behavior are problematic. The OAI public data provide objective physical activity assessments from accelerometer monitoring and longitudinal clinical assessments to pursue the following aims: Aim 1. Describe Daily Sedentary Behavior Characteristics Describe the distribution of daily sedentary behavior characteristics: 1) total sedentary time, 2) maximum duration of sedentary bouts (sessions), 3) sedentary break frequency, and 4) physical activity duration/intensity level during sedentary breaks. Aim 2: Identify Distinct Sedentary Profiles Identify the presence of distinct baseline sedentary profiles (i.e., combinations of sedentary behavior characteristics in Aim 1) and evaluate their distribution. Latent profile analysis will be used to identify sedentary profiles. Aim 3. Association of Sedentary Behavior Characteristics and Profiles with Functional Loss Evaluate the relative strength of association of sedentary behavior characteristics (Aim 1) and sedentary profiles (Aim 2) with subsequent functional loss at year 2. Results from this study will expand the understanding of sedentary behavior characteristics, sedentary profiles, and their association with subsequent functional loss in order to inform the development of more effective interventions to sustain function and independence of older adults.