UNC Wits AIDS Implementation Research and Cohort Analyses Training Grant

描述（由申请人提供）：在超过十年的联合福格蒂和NIAID研究和培训支持我们的两所大学的基础上，UNC-Wits艾滋病实施科学和队列分析培训补助金将培训Wits初级教师和高级学员，并通过在公共卫生的Wits学校创建一个新的实施科学的浓度来加强流行病学硕士学位。南非继续有艾滋病毒流行病，有560万人感染艾滋病毒/艾滋病，是所有国家中最多的，每年有27万人死亡。实施科学对于了解艾滋病毒项目如何运作和制定提高有效性的战略，确定如何有效地扩大已被证明的干预措施，进行研究并为南非政府和国际机构提供知情的答案至关重要。目前将SA受训人员送往海外进行长期培训的方法成本高昂，不可持续，增加了受训人员的风险， 回国后，他们在国内的工作和家庭受到威胁，而且往往要学习与本国没有直接关系的课程。在撒哈拉以南非洲没有实施科学培训方案。来自Wits健康科学学院的学员及其来自不同背景（护理，公共卫生，医学，药学，牙科）的校友将参加由Wits和Wits教师共同教授的3年，12门课程（长期），以获得流行病学硕士或硕士学位，并专注于实施科学。额外的学生将参加至少一个课程（中期和短期）的课程，并获得证书。由Wits SPH教师确定的内容是其课程中的差距，包括数据库开发和管理，纵向分析和因果推理，卫生经济学，公共卫生中的空间分析和GIS，移动卫生，系统分析，监测和评价，定性和形成性研究。为了节省成本，所有课程将在现场授课2周密集块。在第四年和第五年，课程将重新开始，由Wits教师和以前的Fogarty资助的学员承担更多的责任（“培训培训员”）。那些获得硕士或博士学位的人将在现有的长期南非艾滋病毒队列中工作，包括护理权，IeDEA和Hlabisa。先进的学生将采取为期一年的赠款写作计划与提交赠款的期望。长期的可持续性将通过将课程纳入由Wits教师教授的Wits课程来保证。我们承诺在5年内从联合国和Wits获得额外的资金和实物捐助，总额为35万美元。到5年结束时，我们预计将资助20名硕士或硕士生，4名博士毕业生，6名机智教师在特定的课程方法，以及多达160名学生采取至少一个模块。这项建议将增加这种研究培训的深度和广度，并培养足够数量的南非调查人员和智慧教师，他们将进行协同研究。

DESCRIPTION (provided by applicant): Building on more than a decade of joint Fogarty and NIAID research and training support to our two universities, The UNC-Wits AIDS Implementation Science and Cohort Analyses Training Grant will train Wits junior faculty and advanced trainees and strengthen the MSc in Epidemiology by creating a new concentration of implementation science at the Wits School of Public Health. South Africa continues to have an HIV epidemic with 5.6 million living with HIV/ AIDS, the most of any country, and 270,000 deaths annually. Implementation science is crucial to understand how HIV programs are working and develop strategies for improved effectiveness, to determine how proven interventions can be scaled up effectively, to conduct research, and provide informed answers to SA government and international agencies. The current method of sending SA trainees overseas for long term training is costly, not sustainable, increases the risks of the trainees not returning, jeopardizes their jobs and families at home, and often exposes them to courses not directly relevant to their home countries. There are no implementation science training programs in Sub- Saharan Africa. Trainees from Wits Faculty of Health Science schools and its alumni from diverse backgrounds (nursing, public health, medicine, pharmacy, dental) will participate in a 3 year, 12 course curriculum (long- term) co-taught by UNC and Wits faculty leading to an MPH or MSc in Epidemiology with a concentration in Implementation Science. Additional students will take at least one course (medium and short-term) of the curriculum and receive a certificate. The content, identified by the Wits SPH faculty as gaps in their curriculum, include database development and management, longitudinal analysis and causal inference, health economics, spatial analysis and GIS in public health, m-health, systems analysis, monitoring and evaluation, qualitative and formative research. To save on costs, all courses will be taught on site in 2 week intensive blocks. During years 4 and 5, the courses would start over again, with more responsibility taken by the Wits faculty and previous Fogarty funded trainees ("train the trainers"). Those obtaining a Masters or a PhD would work on existing long term South African HIV cohorts including Right to Care, IeDEA, and Hlabisa. Advanced students would take a year-long grant writing program with the expectation of submitting a grant. Long term sustainability would be guaranteed by incorporating the courses into the Wits curriculum taught by Wits faculty. We have commitments of additional funding and in-kind contributions from UNC and Wits totaling $350,000 over 5 years. By the end of the 5 years we expect to have funded 20 MSc or MPH students, 4 PhD graduates, 6 Wits faculty in specific course methodologies, as well as up to 160 students taking at least one module. This proposal will increase the depth and breadth of this research training and develop a critical mass of South African investigators and Wits faculty who will conduct synergistic research.