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Dealing with missing data in HIV prevention trials

Dealing with missing data in HIV prevention trials
处理艾滋病毒预防试验中缺失的数据
批准号:
8605221
负责人:
Ofer Harel
金额:
$17.22万
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-04-09 至 2016-01-31
关键词:
AIDS preventionAIDS/HIV problemAccountingAcquired Immunodeficiency SyndromeAcyclovirAdultAfricanAfrican AmericanAgeAlcohol or Other Drugs useAlcoholsAmericanAttentionBehavior TherapyBehavioralBehavioral ResearchBiologicalBiometryCause of DeathCenters for Disease Control and Prevention (U.S.)CitiesClinicalCommunitiesComplicationCounselingCountryCross-Over StudiesDataDistrict of ColumbiaDouble-Blind MethodDropsEffectivenessEnsureEpidemicFundingFutureGoalsGuidelinesHIVHIV InfectionsHIV SeropositivityHIV prevention trialHIV prevention trials networkHIV-1HealthHealthcareHuman Herpesvirus 2InfectionIntentionInternationalInterventionIntervention StudiesInvestigationLeadLearningLifeLiteratureLongevityLongitudinal StudiesLos AngelesMeasuresMedicalMentored Research Scientist Development AwardMethodologyMethodsMissionNIH Program AnnouncementsNational Institute of Mental HealthNew YorkPersonsPharmaceutical PreparationsPlacebo ControlPlaguePopulationPositioning AttributePre-Post TestsPreventionPrevention ResearchPrevention programPreventive InterventionProceduresProcessQuality of lifeRampRandomizedRandomized Clinical TrialsResearchResearch DesignResearch PersonnelRiskRisk BehaviorsRisk ReductionSamplingSan FranciscoScienceScientistSimplexvirusSiteSouth AfricaTechniquesTestingTrainingUnited StatesUnited States National Institutes of HealthVariantVisitWomanWritingbasedesigneffective interventiongenital herpeshigh riskimprovedintravenous drug usemenmen who have sex with menpreventpublic health relevanceresponsesexsexually activesimulationsocialstatisticstooltransmission processtreatment effectvalacyclovir

项目摘要

项目成果

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相关文献

中文摘要
翻译
描述(由申请者提供):艾滋病毒/艾滋病几十年来一直是一种国际危机。所有目前的研究都表明,短期内不太可能有任何药物治愈,预防是我们可以采用的最好策略。然而,尽管几十年来,预防艾滋病毒/艾滋病一直是国际筹资的目标和主要重点,但我们仍然看到,全球每年新增艾滋病毒/艾滋病病例数量急剧增加。显然,需要更多的关注和研究,以确保我们尽可能使用最好的预防技术。我的长期目标是开发新的方法来推进临床和社区艾滋病行为研究。此外,我的目标是开发新的方法,以加强艾滋病毒预防干预。这一应用程序支持国家精神卫生研究所的使命,为不完整的数据提供方法学,这将被用来帮助制定有效的干预措施,并通过提供培训来定位这名候选人,使其能够参与未来的研究,以改进艾滋病毒预防。 与公共卫生相关:艾滋病毒/艾滋病几十年来一直是一场国际危机。所有目前的研究都表明,短期内不太可能有任何药物治愈,预防是我们可以采用的最好策略。我的长期目标是开发新的方法来推进临床和社区艾滋病行为研究。此外,我的目标是开发新的方法,以加强艾滋病毒预防干预,特别是处理不完整数据的方法。
英文摘要
DESCRIPTION (provided by applicant): HIV/AIDS has been an international crisis for decades. All current research suggests that there is not likely to be any medical cure anytime soon, and that prevention is the best strategy that we can employ. However, notwithstanding that HIV/AIDS prevention has been the goal and primary focus of funding internationally for decades, we still see a sharp increase in the number of new HIV/AIDS cases across the globe annually. Clearly, there needs to be more focus and research dedicated to ensuring that we are using the best prevention techniques possible. My long term goal is to develop new methodologies for advancing clinical and community AIDS behavioral research. In addition, my aim is to develop new methods that will lead to enhanced HIV prevention interventions. This application supports the mission of the National Institute of Mental Health by providing methodologies for incomplete data, this will be used to help develop effective interventions and by providing training to position this candidate to engage in future research to improve the HIV prevention. PUBLIC HEALTH RELEVANCE: HIV/AIDS has been an international crisis for decades. All current research suggests that there is not likely to be any medical cure anytime soon, and that prevention is the best strategy that we can employ. My long term goal is to develop new methodologies for advancing clinical and community AIDS behavioral research. In addition, my aim is to develop new methods that will lead to enhanced HIV prevention interventions, In particular, methods to deal with incomplete data.
期刊论文(26)
专著(0)
科研奖励(0)
会议论文
Brief Report: Rethinking Data Collection for HIV Prevention Trials.
简要报告:重新思考艾滋病毒预防试验的数据收集。
DOI: 10.1097/qai.0000000000001005
发表时间: 2016
期刊: Journal of acquired immune deficiency syndromes (1999)
影响因子: --
作者: [Harel,Ofer, Nazzaro,Valerie]
通讯作者: Nazzaro,Valerie
A Review of Statistical Disclosure Control Techniques Employed by Web-Based Data Query Systems.
基于网络的数据查询系统所采用的统计披露控制技术的回顾。
DOI: 10.1097/phh.0000000000000473
发表时间: 2017
期刊: Journal of public health management and practice : JPHMP
影响因子: --
作者: [Matthews,GregoryJ, Harel,Ofer, AseltineJr,RobertH]
通讯作者: AseltineJr,RobertH
Analyzing clinical trial outcomes based on incomplete daily diary reports.
根据不完整的每日日记报告分析临床试验结果。
DOI: 10.1002/sim.6890
发表时间: 2016
期刊: Statistics in medicine
影响因子: 2
作者: [Thomas,Neal, Harel,Ofer, Little,RoderickJA]
通讯作者: Little,RoderickJA
An examination of data confidentiality and disclosure issues related to publication of empirical ROC curves.
检查与发布经验 ROC 曲线相关的数据保密和披露问题。
DOI: 10.1016/j.acra.2013.04.011
发表时间: 2013
期刊: Academic radiology
影响因子: 4.8
作者: [Matthews,GregoryJ, Harel,Ofer]
通讯作者: Harel,Ofer
共 12 条
    Dealing with missing data in HIV prevention trials
    Dealing with missing data in HIV prevention trials
    Dealing with missing data in HIV prevention trials
    Dealing with missing data in HIV prevention trials