Large-Scale Multi-Omic Analysis and Risk Prediction of Complex Human Disease

医学的一个主要目的是预防疾病，这通常比治疗已经存在的疾病更成功和更具成本效益。常见的疾病，如自身免疫性疾病和心血管疾病，都有诱发遗传的基础。我们将对腹腔疾病和心血管疾病的大型数据集进行遗传分析，以更好地识别风险增加的个体，并更好地了解遗传学影响风险的潜在生物学过程。

A major aim of medicine is to prevent disease, which is often more successful and cost-effective than treating an already existing condition. Common diseases, such as autoimmune and cardiovascular diseases, have a predisposing genetic basis. We will conduct genetic analysis of large datasets of coeliac disease and cardiovascular disease to better identify individuals at increased risk and to better understand the underlying biological processes through which genetics act to affect one's risk.