Einstein's Nathan Shock Center of Excellence in Basic Biology of Aging

爱因斯坦-内森休克中心(E-NSC)的研究开发核心利用资源 允许为18项试点研究和3项可行性研究提供资金，并为核心技术开发提供3项奖励。的 这些，5项P&F研究导致了NIH的资助，5项尚待资助(有些成绩突出)； 此外，有11份出版物是2013年前资助的研究成果。这些P&F研究旨在和 将继续在爱因斯坦和布朗大学“迷你NSC”加强和支持E-NSC科学。我们 已经扩大了核心，以确定有潜力向老龄化研究和 通过助学金申请提供持续的指导，并帮助初级教员和研究人员 老龄化研究。我们还为接受P&F资助的人提供关于衰老生物学的正式教育，并 任何想要从部分或全部正规研究生课程中受益的人。我们认为这样的活动 CORE加强了E-NSC社区，吸引了新的研究人员参与与老龄化相关的研究，并成功 推动老龄化相关领域的新研究。衰老研究是爱因斯坦研究的一个重要组成部分 科学界，如该研究所承诺每年提供高达150,000美元的匹配 用于试点赠款的资金。这将允许在任何给定的情况下最多资助3到5个P&F项目和3个迷你P&F项目 并在下一个赠款期间向研究人员提供较少的资金，用于研究资源的核心使用 在正式的P&F申请前获得初步数据。

The Research Development Core of the Einstein- Nathan Shock Center (E-NSC) has leveraged resources to allow funding of 18 pilot and 3 feasibility (P&F) studies and 3 awards for development of Core technologies. Of these, 5 P&F studies led to NIH funding and 5 have pending funding (some with outstanding scores); in addition, 11 publications, resulted from studies funded before 2013. These P&F studies are designed to and will continue to enhance and support E-NSC science at Einstein and at the Brown University `mini-NSC'. We have expanded the Core to identify new faculty who have potential for `conversion' to aging research and provide continuous mentoring through grant applications and to assist junior faculty and investigators new to aging research. We also provide formal education in the biology of aging to recipients of P&F funding and anyone who wants to benefit from part or all of the formal graduate course. We believe that activities of this Core strengthen the E-NSC community, attract new investigators to aging-related research, and successfully promote new research endeavors in aging-related areas. Aging research is a key component of the Einstein scientific community, as shown by the Institution's commitment to provide up to $150,000 annually in matching funds for pilot grants. This will permit the funding of up to 3 to 5 P&F projects and 3 mini-P&Fs in any given year and provide smaller amounts to investigators in this next grant period for Research Resource Core use to obtain preliminary data before formal P&F application.