Minority Institutional Research Training Program (T32)

 描述(由申请人提供)：这是20年前在新墨西哥大学(UNM)建立的心血管研究培训计划(CRTP)的竞争性续签申请的重新提交。它为来自代表性不足背景的博士后和博士后实习生提供了获得心血管生物学研究培训的机会。这笔赠款也促进了新墨西哥大学心血管科学研究和培训综合计划的发展。CRTP架起了基础科学和临床科学的桥梁，并促进了学科之间新的富有成效的合作。这一研究和培训重点领域与新墨西哥州特别相关，那里心血管相关疾病的发病率很高，特别是在西班牙裔和美洲原住民人口中。在赠款的任期内，制定了几个新的计划，将UNM健康科学中心(HSC)的心血管科学研究统一起来，包括与医学院和药学院的研究人员组成血管生理学小组。此外，自最初为该奖项提供资金以来，UNM HSC已经确定了标志性的研究项目，其中包括一项专注于心血管和代谢疾病(CVMD)的研究项目。这一研究领域从研究办公室获得特别资金，以支持试点研究并加强其成员之间的合作项目。这项资助的所有导师都是这项签名计划的成员，其中T32的一名关键成员担任CVMD计划的负责人。生物医学科学研究生课程的结构也促进了合作研究，该课程在UNM HSC内提供了一个统一的培训环境。研究生课程是非院系的，在第一年提供广泛的生物医学科学基础上的跨学科培训，然后是所选学科的深入培训。目前申请的目标是建立在这一框架之上，并提高我们在招聘和培训来自代表性不足背景的科学家方面的成功。为了实现后一项目标，我们设计了招生策略，力求将我们的课程与该地区UNM和合作机构现有的以少数族裔为基础的本科生和硕士课程相结合。我们还将促进与临床医生科学家在最近资助的 临床和翻译科学中心(CTSC)为翻译研究培训提供新的机会。CTSC的领导人是这一T32的导师，并将帮助协调CTSC为博士后和博士后学员提供的研究机会。来自基础科学系和临床系的20名富有成效和协作精神的教职员工将担任教员导师。CRTP将继续每年支持8个博士后和2个博士后职位。计划的聘期为博士后学生2-3年，博士后实习生2年，后续由个人培训奖学金或职业指导奖提供支持。(摘要结束)

 DESCRIPTION (provided by applicant): This is a resubmission of a competitive renewal application for a Cardiovascular Research Training Program (CRTP) that was established twenty years ago at the University of New Mexico (UNM). It has served to provide opportunities for predoctoral and postdoctoral trainees from underrepresented backgrounds to gain research training in cardiovascular biology. This grant has also been a catalyst for the development of an integrated program of research and training in cardiovascular sciences at UNM. The CRTP has bridged the basic and clinical sciences and has fostered new productive collaborations between disciplines. This area of research and training emphasis has particular relevance to the state of New Mexico where the incidence of cardiovascular-related disease is high, especially in the Hispanic and Native American populations. During the tenure of the grant, several new programs have evolved that unify research in the cardiovascular sciences at the UNM Health Sciences Center (HSC), including the formation of the Vascular Physiology Group with researchers from the School of Medicine and the College of Pharmacy. In addition, since the initial funding of the award, the UNM HSC has identified signature research programs including one focused on Cardiovascular and Metabolic Disease (CVMD). This area of research receives special funds from the Office of Research to support pilot studies and to enhance collaborative projects between its members. All of the mentors on this grant are members of this signature program with a key member of the T32 serving as the leader of the CVMD program. Collaborative research is also facilitated by the structure of the Biomedical Sciences Graduate Program that offers a unified training environment within the UNM HSC. The graduate program is non-departmental and provides interdisciplinary training over a broad base of biomedical science in the first year, followed by in-depth training in the chosen discipline. The goals of th current application are to build upon this framework and to improve our success in recruiting and training scientists from underrepresented backgrounds. To foster this latter objective, we have designed recruitment strategies that seek to improve integration of our program with existing minority-based undergraduate and master's programs at UNM and partner institutions in the region. We will also promote collaborations with clinician scientists in the recently funded Clinical and Translational Sciences Center (CTSC) to provide new opportunities for training in translational research. Leaders of the CTSC are mentors on this T32 and will help to coordinate research opportunities in the CTSC for both pre- and post-doctoral trainees. Twenty productive and collaborative faculty members from both basic science and clinical departments will serve as faculty mentors. The CRTP will continue to support eight predoctoral and two postdoctoral positions per year. Planned appointment durations are 2-3 years for predoctoral students and 2 years for postdoctoral trainees, with subsequent support provided by individual training fellowships or mentored career awards. (End of Abstract)