May I Help You? An Avatar Health Concierge for HIV-infected African American MSM

 描述(由申请人提供)：此申请响应总统的艾滋病毒护理连续倡议，通过开发一种基于理论的阿凡达移动电话干预，在护理的五个阶段中的三个阶段，让年轻的艾滋病毒阳性的非裔美国男性与男性发生性关系(AAMSM)：(1)保留，(2)遵守HAART，和(3)抑制病毒，从而提高从事护理的艾滋病毒感染者的比例。这项干预措施将最大限度地提高遵循健康行为的可能性，从而使患者受益(发病率、死亡率和对S病毒的抵抗力降低)和人群受益(减少艾滋病毒传播)。男男性接触者占男性新感染艾滋病毒的四分之三以上，其中近一半是AAMSM。此外，他们不太可能接受高效的抗逆转录病毒治疗和 有病毒抑制作用。我们将系统地开发并评估基于理论的创新的阿凡达移动电话应用程序的可行性、可接受性、利用率和初步影响，以使感染艾滋病毒的年轻AAMSM参与艾滋病毒护理连续过程的多个阶段。该干预借鉴了信息动机行为技能模型，该模型侧重于影响一个人的行为技能、行为和预期健康结果的信息和动机之间的反馈。阿凡达将鼓励与信息和功能的互动，以促进与艾滋病毒关怀连续体的接触，提供基本的艾滋病毒信息，提供激励声明，促进与医疗保健的互动，可视化实验室结果，并鼓励、解释甚至说明相关的行为技能。我们将(1)开发基于阿凡达的手机应用程序；(2)与6个感染艾滋病毒的AAMSM(N=24)的4个连续焦点小组进行参与性形成性研究，以修订基于阿凡达的应用程序，以确保目标人群最大限度地接受；(3)评估该应用程序，以确定该应用程序的接受度、可行性、利用率和初步效果，包括抽血和艾滋病毒临床回访依从性、服药数量和自我报告的依从性，以及对50名感染艾滋病毒的AAMSM(5名测试者和45名试点受试者)和病毒载量的抑制；以及(4)根据试点研究参与者的调查和口头输入修改该应用程序。如果成功，阿凡达随后将在AAMSM的大规模随机对照试验中进行测试。

 DESCRIPTION (provided by applicant): This application responds to the President's HIV Care Continuum Initiative to improve the proportion of HIV- infected persons engaged in care by developing a theory-based Avatar mobile phone intervention that engages young HIV-positive African American men who have sex with men (AAMSM) in three of the five stages of care: (1) retention, (2) HAART adherence, and (3) viral suppression. The intervention will maximize the likelihood of compliance with healthy behavior leading to both patient benefits (decreased morbidity, mortality and resistant viru s) and population benefits (decreased HIV transmission). MSM account for more than three-fourths of new HIV infections among men and nearly half of these are AAMSM. In addition, they are less likely to take highly active antiretroviral therapy and have viral suppression. We will systematically develop and then evaluate the feasibility, acceptability, utilization, and preliminary impact of a theory-based innovative Avatar mobile phone application to engage young HIV-infected AAMSM in multiple stages of the HIV Care Continuum. The intervention draws on the Information Motivation Behavioral Skills Model that focuses on feedback between information and motivation that affect one's behavioral skills, behaviors, and desired health outcomes. The Avatar will encourage interaction with information and functions that promote engagement with the HIV Care Continuum, provide fundamental HIV information, provide motivating statements, facilitate interaction with healthcare, visualize laboratory results, and encourage, explain, and even illustrate relevant behavioral skills. We will (1) Develop an Avatar-based mobile phone application; (2) Perform participatory formative research with 4 sequential focus groups of 6 HIV-infected AAMSM (N=24) to revise the Avatar-based app in order to ensure maximum acceptability among the target population; (3) Evaluate the app to determine acceptability, feasibility, utilization and preliminary effects including bloo draw and HIV clinic return visit compliance, pill count and self reported adherence, and viral load suppression in 50 HIV-infected AAMSM (5 beta testers and 45 pilot subjects) and (4); Revise the app based on survey and oral input from pilot study participants. If successful, the Avatar will be subsequently tested in a large scale randomized controlled trial with AAMSM.