Aberrant Signalling in Leukaemia

该计划研究控制血细胞形成的机制，以及异常如何在白血病中发挥作用，这是一个全球性的重大健康问题。尽管取得了一些进展，但仍存在两个主要问题：控制白血病的进展和复发。该项目通过结合正常血液和白血病细胞功能的研究、药物设计和临床试验来解决这两个主要问题，确保从发现到患者受益的直接途径。

This Program studies the mechanisms that control blood cell formation and how abnormalities play a role in leukaemia, a significant health problem worldwide. Despite some improvements, two major problems remain: controlling progression of leukaemia and relapse. The Program tackles these two major issues with the combination of studies of normal blood and leukaemia cell function, drug design and clinical trials ensuring a direct pathway from discovery to patient benefit.