ASPREE-D; Aspirin in the prevention of depression in the elderly

ASPREE（阿司匹林减少老年人事件）研究是一项为期5年的随机对照试验，在19，000名70岁以上的健康人中使用阿司匹林（每日100 mg）或安慰剂。我们的目标是增加现有的基础设施，以确认阿司匹林的效用，预防老年人抑郁症（ASPREE-D）。ASPREE-D的主要目的是确定在70岁以上的健康个体中，使用低剂量阿司匹林是否会降低抑郁症新发发作的发生率。

The ASPREE (ASPirin in Reducing Events in the Elderly) study is a 5 year RCT of aspirin (100mg daily) or placebo in 19,000 healthy people over 70. We aim to augment the existing infrastructure of ASPREE in order to confirm the utility of aspirin for the prevention of depression in the elderly (ASPREE-D). The primary aim of ASPREE-D is to determine if use of low-dose aspirin reduces the incidence of de-novo episodes of depression in healthy individuals over 70 years of age.