The Preemie-Pacer: An Innovative Bottle to Promote Safe and Efficient Oral Feeding in Preterm Infants

项目总结/摘要 仅在美国，每年就有45万早产儿。早产儿通常需要 新生儿重症监护室的护理。为了出院，最后的里程碑之一 新生儿重症监护室的最后一项措施是口服口服喂养对早产儿来说可能是一个挑战 因为它们还没有成熟到可以协调吮吸、吞咽和呼吸的程度。很多婴儿 会吮吸和吞咽，他们无法呼吸会导致危险的生理波动。帮助 由此可以使用起搏技术。谨慎的护理人员可以间歇性地将奶瓶奶嘴从奶瓶中拔出。 婴儿的嘴，以鼓励呼吸和恢复。这可能会破坏喂食过程， 会消耗大量的能量，这会给父母带来压力。为了解决这个问题，Preemie-Pacer 瓶子正在开发中。Preemie-Pacer有一个内部机制，可以中断乳汁流向 乳头间歇地使婴儿暂停和呼吸。 这个项目的长期目标是开发一种创新的奶瓶，将解决早产的问题， 婴儿在早期经口喂养期间的经验，允许安全有效地进行早期喂养。项目 目的是开发Preemie-Pacer原型并评估Preemie-Pacer的可接受性 早产儿的父母和新生儿重症监护室的卫生保健专业人员。为了实现这一点， Preemie-Pacer的概念将转换为2D，然后是3D图纸。将制作原型， 当它们不符合形式和功能的既定设计标准时，进行修改。测试将在 一个吸奶器，和4个修改的原始原型，预计在所有既定的设计标准 得到满足。新生儿重症监护室专业人员和家长的焦点小组将被用来评估 可接受性，并确定额外的设计需求，预计最终修改的 根据家长和医护人员的反馈意见制作样机，以优化设计。这 这项工作将为II期临床试验奠定基础。 Preemie-Pacer可以对早产儿接受的护理产生重大影响。如果安全有效 甚至可以提前几天实现经口喂养，可以节省大量的医疗保健费用，而且婴儿 可以提早出院回家。此外，父母可能会有更多的成功， 喂养高危早产儿的信心。

PROJECT SUMMARY/ABSTRACT There are 450,000 infants born preterm each year in the United States alone. Preterm infants often necessitate care in the neonatal intensive care unit. One of the final milestones to be achieved in order to be discharged from the neonatal intensive care unit is oral feeding. Oral feeding can be a challenge for infants born preterm as they do not have the maturity that allows for coordinated sucking, swallowing, and breathing. Many infants will suck and swallow, and their failure to breathe will result in dangerous physiological fluctuations. To help with this, pacing techniques can be used. Cautious caregivers can intermittently pull the bottle nipple out of the infant’s mouth to encourage breathing and recovery. This can be disruptive to the feeding process, can result in significant energy expenditure, and can be stressful for parents. To address this problem, the Preemie-Pacer bottle is being developed. The Preemie-Pacer has an internal mechanism that interrupts the flow of milk to the nipple intermittently to enable the infant to pause and breathe. The long term goal of this project is to develop an innovative bottle that will address the problems that preterm infants experience during early oral feeding, allowing early feeds to be done safely and efficiently. The project aims are to develop prototypes of the Preemie-Pacer and to assess the acceptability of the Preemie-Pacer among parents of preterm infants and neonatal intensive care unit health care professionals. To achieve this, the concept of the Preemie-Pacer will be converted to 2D and then 3D drawings. Prototypes will be made and modified when they do not meet established design criteria for form and function. Testing will be conducted on a breast pump, and 4 modifications of the original prototype are expected before all established design criteria are met. Focus groups of neonatal intensive care unit professionals and parents will be used to assess the acceptability and to determine additional design needs, and it is expected that one final modification of the prototype will be made after parent and health care professional feedback in order to optimize the design. This work will set the stage for clinical trials in Phase II. The Preemie-Pacer can have a significant impact on the care that preterm infants receive. If safe and efficient oral feeding can be achieved even a few days earlier, significant health care dollars can be saved and infants can be discharged to their homes earlier. In addition, parents can potentially have more success and confidence in feeding their high-risk preterm infants.