Administrative Core

项目总结--行政核心 行政核心将监督P01赠款的行政和财务活动。整体而言 管理核心的目标是提供集中的科学、管理和财务 管理和监督我们的计划项目(P01)赠款，题为“功能基因组学和DEC-Tec，以 确定特定于生殖细胞的避孕药。行政核心将1)促进内部的科学互动 P01资助团队以及我们的P01团队与其他避孕领域的研究人员之间的合作，2) 领导P01调查人员保持高质量、成功的研究和核心活动，并完成他们的 具体的目的和目标，以及3)促进可逆的男性和女性避孕药具进入 临床试验。行政核心将为跟踪赠款资金的使用情况提供支持，并准备所有 与P01相关的报告和未来的赠款申请。马丁·M·马祖克博士将是主要的 个人负责的行政核心，将提供行政和科学的管理 P01补助金，并将负责就与研究优先事项或问题有关的政策事项作出决定 在项目或核心内以及P01赠款的整体运作方面。研究咨询 委员会(多学科内部和外部科学和行政成员和领导人)将 向Matzuk博士、项目和核心提供建议和指导。Matzuk博士将每月由 业务委员会关于集团内资源分配和资金支付的具体规定 用于增加或替换人员、设备或其他需求。行政核心将协调 研究咨询委员会(RAC)年会。RAC将指导每个项目和 12月-技术核心关于所选避孕目标的“通过”和“不通过”的决定，后续目标 筛查，以及小分子避孕药的开发计划。此外，行政核心将 协调RAC每半年召开一次电话会议。行政支助将由两个人提供 有才华的专业人士。约翰·W·纳尔逊博士，药物发现中心的业务经理。 高级助学金专家维罗妮卡·阿吉拉尔将提供多重行政和财务管理 服务。行政核心将设在贝勒库伦大楼的2楼，交通便利 医学院(BCM)，距离BCM项目调查人员很近。所有项目负责人和核心人员 董事，包括大阪大学的董事，将可以接触到财务、人事、网络和 计算机服务。这三个项目和核心B(DEC-Tec)将平等地利用行政核心。这个 行政核心和RAC将指导P01项目和核心领导做出推进的关键决策 或停止每一次避孕开发运动，这将对这次P01的成功做出重大贡献 资助建议和创造多种新型生殖细胞特异性避孕药。

PROJECT SUMMARY - ADMINISTRATIVE CORE The Administrative Core will oversee the administrative and financial activities of the P01 grant. The overall objective of the Administrative Core is to provide centralized scientific, administrative, and financial management and oversight of our program project (P01) grant entitled “Functional genomics and DEC-Tec to identify germ cell–specific contraceptives.” The Administrative Core will 1) foster scientific interactions within the P01 grant team and between our P01 team and other investigators working in the field of contraception, 2) lead the P01 investigators to maintain high-quality, successful research and core activities and fulfill their Specific Aims and objectives, and 3) promote the movement of reversible male and female contraceptives into clinical trials. The Administrative Core will provide support for tracking grant fund utilization and prepare all reports and future grant submissions associated with the P01. Dr. Martin M. Matzuk will be the primary individual responsible for the Administrative Core, will provide administrative and scientific management of the P01 grant, and will be responsible for decisions regarding policy matters relating to research priorities or issues within the Projects or Cores as well as the overall operation of the P01 grant. The Research Advisory Committee (multidisciplinary internal and external scientific and administrative members and leaders) will provide advice and direction to Dr. Matzuk, Projects, and Cores. Dr. Matzuk will be advised monthly by the Operations Committee regarding the specifics of resource allocation within the group and fund disbursement for additional or replacement personnel, equipment, or other needs. The Administrative Core will coordinate the annual meeting of the Research Advisory Committee (RAC). The RAC will guide each Project and the DEC-Tec Core on decisions of “Go” versus “No Go” for the contraceptive targets chosen, follow-up targets to screen, and the small-molecule contraceptive development program. Additionally, the Administrative Core will coordinate a semi-annual conference call meeting of the RAC. Administrative support will be furnished by two talented professionals. Dr. John W. Nelson, Business Manager in the Center for Drug Discovery, and Ms. Veronica Aguilar, a Senior Grants Specialist, will provide multiple administrative and financial management services. The Administrative Core will be conveniently located on the 2nd floor of the Cullen Building at Baylor College of Medicine (BCM) in close proximity to the BCM Project Investigators. All Project Leaders and Core Directors, including those at Osaka University, will have access to financial, personnel, networking, and computer services. The three Projects and Core B (DEC-Tec) will utilize the Administrative Core equally. The Administrative Core and RAC will guide the P01 Project and Core Leaders on critical decisions for advancing or halting each contraceptive development campaign and will contribute significantly to the success of this P01 grant proposal and the creation of multiple novel germ cell-specific contraceptives.