Lipoxins protect against diabetes associated atherosclerosis

血管疾病是糖尿病患者死亡的主要原因。目前的治疗方法是不够的，因为心血管疾病仍然占糖尿病患者死亡率的70%以上。我们令人兴奋的新数据表明，一种新的内源性小分子(脂氧素A4)对血管细胞内驱动动脉粥样硬化的病理过程具有保护作用。这代表了一种很有希望的方法来对抗糖尿病并发症，如糖尿病相关的动脉粥样硬化。

Vascular disease is a major cause of mortality in diabetes. Current treatments are inadequate as cardiovascular disease still represents more than 70% of mortality in people with diabetes. Our exciting new data demonstrate that a novel endogenous small molecule (Lipoxin A4) has protective effects against the pathological processes within vascular cells that drive atherosclerosis. This represents a promising approach to combat diabetic complications such as diabetes-associated atherosclerosis.