Local Sleep in the Awake Brain: An Underlying Cause of Neurobehavioural Deficits in Sleep Apnea?

阻塞性睡眠呼吸暂停（OSA）是一种常见的睡眠障碍，严重影响白天的功能，导致过度嗜睡，注意力和思维问题。目前，阻塞性睡眠呼吸暂停患者认知功能障碍的原因（包括注意力缺失和表现缺陷）尚不清楚。在清醒状态下，神经元群可以像在睡眠中一样短暂地“脱机”。这些“局部睡眠”可以解释阻塞性睡眠呼吸暂停综合症患者任务表现受损的原因。

Obstructive sleep apnea (OSA) is a common sleep disorder which significantly impacts daytime functioning leading to excessive sleepiness, and problems with attention and thinking. Currently, the causes for cognitive impairment in OSA (including attentional lapses and performance deficits) are poorly understood. In the awake state, groups of neurons can briefly go “offline” as they do in sleep. These periods of “local sleep” may explain impaired task performance in OSA.