Network Lead Academic Participating Site: Memorial Sloan Kettering Cancer Center

项目摘要/摘要 这份申请是纪念斯隆·凯特琳癌症中心(MSK)提出的续批U10CA180791的建议 为了保持其作为NCI国家临床网络领先学术参与网站的地位 试验网络(NCTN)。该项目的长期目标和具体目标是让MSK继续 对NCTN试验的开发以及NCTN和NCI的活动提供科学领导 科学指导委员会，为NCTN试验的患者收益做出贡献，并为 临床试验研究的初级研究员。 MSK拥有经过验证的资源，可以为网络带来强大的科学驱动的研究，并 参与其他网络参与者提出的研究。MSK拥有一支多学科团队 致力于转化性研究的研究人员，可以参与临床的大量患者群体 试验，以及一流的基础设施，以继续成功地支持这种试验。MSK是 肿瘤学和NRG肿瘤学临床试验联盟，以及ECOG- 阿克林。这个网络领先学术网站UG1的多名首席研究员都是经验丰富的领导者 在网络小组中，有实现这些科学、收益和指导目标的记录。 此外，作为一个只专注于癌症的大型中心，MSK拥有特殊的专业知识和承诺 NCTN评估罕见肿瘤的任务。 好了！

Project Summary/Abstract This application is Memorial Sloan Kettering Cancer Center's (MSK's) proposal to renew grant U10CA180791 in order to maintain its status as a Network Lead Academic Participating Site for the NCI National Clinical Trials Network (NCTN). The long-term objectives and specific aims of this project are for MSK to continue to provide scientific leadership in the development of NCTN trials and the activities of the NCTN and NCI Scientific Steering Committees, to contribute to patient accrual on NCTN trials, and to provide mentorship to junior investigators in clinical trial research. MSK has the proven resources to both bring strong scientifically driven studies to the network and to participate in studies brought forth by other network participants. MSK has a multidisciplinary team of investigators committed to translational research, a large patient population amenable to participation in clinical trials, and superb infrastructure to continue to successfully support such trials. MSK is a Main Member of Alliance for Clinical Trials in Oncology and NRG Oncology, as well as a Scientific Main Member of ECOG- ACRIN. The multiple Principal Investigators of this Network Lead Academic Site UG1 are experienced leaders in the network groups, with a track record of meeting these scientific, accrual, and mentoring aims. Furthermore, as a large center focused solely on cancer, MSK has a particular expertise and commitment to the NCTN mission of evaluating rare tumors. !